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Targeting mechanisms of tailed bacteriophages
Phages differ substantially in the bacterial hosts that they infect. Their host range is
determined by the specific structures that they use to target bacterial cells. Tailed phages …
determined by the specific structures that they use to target bacterial cells. Tailed phages …
Killing in the name of: T6SS structure and effector diversity
The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to
optimize their environment, including deploying the type VI secretion system (T6SS). Acting …
optimize their environment, including deploying the type VI secretion system (T6SS). Acting …
Type VI Secretion System in Pathogenic Escherichia coli: Structure, Role in Virulence, and Acquisition
F Navarro-Garcia, F Ruiz-Perez, Á Cataldi… - Frontiers in …, 2019 - frontiersin.org
Bacterial pathogens utilize a myriad of mechanisms to invade mammalian hosts, damage
tissue sites, and evade the immune system. One essential strategy of Gram-negative …
tissue sites, and evade the immune system. One essential strategy of Gram-negative …
Assembly and subcellular localization of bacterial type VI secretion systems
Bacteria need to deliver large molecules out of the cytosol to the extracellular space or even
across membranes of neighboring cells to influence their environment, prevent predation …
across membranes of neighboring cells to influence their environment, prevent predation …
Polymorphic toxins and their immunity proteins: diversity, evolution, and mechanisms of delivery
All bacteria must compete for growth niches and other limited environmental resources.
These existential battles are waged at several levels, but one common strategy entails the …
These existential battles are waged at several levels, but one common strategy entails the …
Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability
Acinetobacter baumannii has emerged as an important nosocomial pathogen, particularly
for patients in intensive care units and with invasive indwelling devices. The most recent …
for patients in intensive care units and with invasive indwelling devices. The most recent …
In situ architecture, function, and evolution of a contractile injection system
Contractile injection systems mediate bacterial cell-cell interactions by a bacteriophage tail–
like structure. In contrast to extracellular systems, the type 6 secretion system (T6SS) is …
like structure. In contrast to extracellular systems, the type 6 secretion system (T6SS) is …
[HTML][HTML] Advances in cryo-electron tomography and subtomogram averaging and classification
P Zhang - Current opinion in structural biology, 2019 - Elsevier
Highlights•Cryo-electron tomography (cryoET) subtomogram averaging has emerged as a
structural biology method for sparse and heterogenerous sampls.•CryoET subtomogram …
structural biology method for sparse and heterogenerous sampls.•CryoET subtomogram …
Structure of a bacterial Rhs effector exported by the type VI secretion system
The t ype VI s ecretion s ystem (T6SS) is a widespread protein export apparatus found in
Gram-negative bacteria. The majority of T6SSs deliver toxic effector proteins into competitor …
Gram-negative bacteria. The majority of T6SSs deliver toxic effector proteins into competitor …
Mechanism of loading and translocation of type VI secretion system effector Tse6
D Quentin, S Ahmad, P Shanthamoorthy… - Nature …, 2018 - nature.com
The type VI secretion system (T6SS) primarily functions to mediate antagonistic interactions
between contacting bacterial cells, but also mediates interactions with eukaryotic hosts. This …
between contacting bacterial cells, but also mediates interactions with eukaryotic hosts. This …