Reviewing the state of biosensors and lab-on-a-chip technologies: Opportunities for extreme environments and space exploration

S Cinti, S Singh, G Covone, L Tonietti… - Frontiers in …, 2023 - frontiersin.org
The space race is entering a new era of exploration, in which the number of robotic and
human missions to various places in our solar system is rapidly increasing. Despite the …

Catalytic/protective properties of martian minerals and implications for possible origin of life on Mars

T Fornaro, A Steele, JR Brucato - Life, 2018 - mdpi.com
Minerals might have played critical roles for the origin and evolution of possible life forms on
Mars. The study of the interactions between the “building blocks of life” and minerals …

Impact-induced amino acid formation on Hadean Earth and Noachian Mars

Y Takeuchi, Y Furukawa, T Kobayashi, T Sekine… - Scientific reports, 2020 - nature.com
Abiotic synthesis of biomolecules is an essential step for the chemical origin of life. Many
attempts have succeeded in synthesizing biomolecules, including amino acids and …

Prebiotic synthesis initiated in formaldehyde by laser plasma simulating high-velocity impacts

M Ferus, F Pietrucci, AM Saitta, O Ivanek… - Astronomy & …, 2019 - aanda.org
Context. It is well known that hydrogen cyanide and formamide can universally be
considered as key molecules in prebiotic synthesis. Despite the fact that formamide has …

[HTML][HTML] Astrochemistry and astrobiology: materials science in wonderland?

M d'Ischia, P Manini, M Moracci, R Saladino… - International Journal of …, 2019 - mdpi.com
Astrochemistry and astrobiology, the fascinating disciplines that strive to unravel the origin of
life, have opened unprecedented and unpredicted vistas into exotic compounds as well as …

Aminomalononitrile inspired prebiotic chemistry as a novel multicomponent tool for the synthesis of imidazole and purine derivatives with anti-influenza A virus activity

BM Bizzarri, A Fanelli, L Botta, M De Angelis… - RSC …, 2021 - pubs.rsc.org
Amino imidazole carbonitrile derivatives decorated with α-amino acid side-chains have
been synthesized by a multicomponent microwave assisted reaction inspired by the …

[HTML][HTML] Prebiotic organic chemistry of formamide and the origin of life in planetary conditions: What we know and what is the future

BM Bizzarri, R Saladino, I Delfino… - International Journal of …, 2021 - mdpi.com
The goal of prebiotic chemistry is the depiction of molecular evolution events preceding the
emergence of life on Earth or elsewhere in the cosmos. Plausible experimental models …

A Three‐Way Regioselective Synthesis of Amino Acid Decorated Imidazole, Purine and Pyrimidine Derivatives by Multicomponent Chemistry Starting from Prebiotic …

BM Bizzarri, A Fanelli, S Cesarini… - European Journal of …, 2022 - Wiley Online Library
Amino acid decorated imidazole, pyrimidine and purine derivatives, resembling analogues
of peptide nucleic acid's building blocks, have been synthesized by a three‐way …

Multicomponent synthesis of diaminopurine and guanine PNA's analogues active against influenza a virus from prebiotic compounds

BM Bizzarri, A Fanelli, S Ciprini, A Giorgi… - ACS …, 2022 - ACS Publications
Peptide nucleic acids (PNAs) play a key role in prebiotic chemistry as a chimera between
RNA and proteins. We developed an alternative synthesis of bioactive PNA's diaminopurine …

Chemical evolution: from formamide to nucleobases and amino acids without the presence of catalyst

V Enchev, I Angelov, I Dincheva… - Journal of …, 2021 - Taylor & Francis
Abiotic synthesis of nucleobases and amino acids is of critical importance as it sheds light
on potential prebiotic chemical reactions. During thermal decomposition of formamide in …