Brain–gut–microbiome interactions in obesity and food addiction

A Gupta, V Osadchiy, EA Mayer - Nature Reviews Gastroenterology & …, 2020 - nature.com
Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

The prevalence of food addiction as assessed by the Yale Food Addiction Scale: a systematic review

KM Pursey, P Stanwell, AN Gearhardt, CE Collins… - Nutrients, 2014 - mdpi.com
Obesity is a global issue and it has been suggested that an addiction to certain foods could
be a factor contributing to overeating and subsequent obesity. Only one tool, the Yale Food …

Which foods may be addictive? The roles of processing, fat content, and glycemic load

EM Schulte, NM Avena, AN Gearhardt - PloS one, 2015 - journals.plos.org
Objectives We propose that highly processed foods share pharmacokinetic properties (eg
concentrated dose, rapid rate of absorption) with drugs of abuse, due to the addition of fat …

Early life adversity and health‐risk behaviors: proposed psychological and neural mechanisms

KA Duffy, KA McLaughlin… - Annals of the New York …, 2018 - Wiley Online Library
Early life adversity (ELA) is associated with poorer health in adulthood, an association
explained, at least in part, by increased engagement in health‐risk behaviors (HRBs). In this …

Lower urinary tract symptoms in depression: a review

DJ Anderson, A Aucoin, CR Toups… - Health psychology …, 2023 - pmc.ncbi.nlm.nih.gov
Lower Urinary Tract Symptoms (LUTS) are frequently present in the general population as
patients age with approximately a third of individuals experiencing LUTS during their …

Shared and unique mechanisms underlying binge eating disorder and addictive disorders

EM Schulte, CM Grilo, AN Gearhardt - Clinical psychology review, 2016 - Elsevier
Scientific interest in “food addiction” is growing, but the topic remains controversial. One
critique of “food addiction” is its high degree of phenotypic overlap with binge eating …

An examination of the food addiction construct in obese patients with binge eating disorder

AN Gearhardt, MA White, RM Masheb… - … Journal of Eating …, 2012 - Wiley Online Library
Objective: This study examined the psychometric properties of the Yale food addiction scale
(YFAS) in obese patients with binge eating disorder (BED) and explored its association with …

Obesity and the brain: how convincing is the addiction model?

H Ziauddeen, IS Farooqi, PC Fletcher - Nature Reviews Neuroscience, 2012 - nature.com
An increasingly influential perspective conceptualizes both obesity and overeating as a food
addiction accompanied by corresponding brain changes. Because there are far-reaching …

Personal responsibility and obesity: a constructive approach to a controversial issue

KD Brownell, R Kersh, DS Ludwig, RC Post… - Health …, 2010 - healthaffairs.org
The concept of personal responsibility has been central to social, legal, and political
approaches to obesity. It evokes language of blame, weakness, and vice and is a leading …

The role of reward circuitry and food addiction in the obesity epidemic: An update

SJ Leigh, MJ Morris - Biological psychology, 2018 - Elsevier
The increasing worldwide prevalence of obesity is partially related to the ready availability of
highly palatable foods which increases the incidence of hedonic, non-homeostatic feeding …