Apolipoprotein E binding drives structural and compositional rearrangement of mRNA-containing lipid nanoparticles
Emerging therapeutic treatments based on the production of proteins by delivering mRNA
have become increasingly important in recent times. While lipid nanoparticles (LNPs) are …
have become increasingly important in recent times. While lipid nanoparticles (LNPs) are …
Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
M Yanez Arteta, T Kjellman… - Proceedings of the …, 2018 - National Acad Sciences
The development of safe and efficacious gene vectors has limited greatly the potential for
therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) …
therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) …
Hybrid biopolymer and lipid nanoparticles with improved transfection efficacy for mRNA
Hybrid nanoparticles from lipidic and polymeric components were assembled to serve as
vehicles for the transfection of messenger RNA (mRNA) using different portions of the …
vehicles for the transfection of messenger RNA (mRNA) using different portions of the …
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein
N Davies, D Hovdal, N Edmunds, P Nordberg… - … Therapy-Nucleic Acids, 2021 - cell.com
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based
drugs but have predominantly been investigated for intravenous and intramuscular …
drugs but have predominantly been investigated for intravenous and intramuscular …
Upgrade of the small-angle neutron scattering diffractometer SANS-J at JRR-3
T Kumada, R Motokawa, Y Oba… - Journal of Applied …, 2023 - journals.iucr.org
The small-angle neutron scattering diffractometer SANS-J at the research reactor JRR-3,
Tokai, Japan has been upgraded. A 3He front detector was installed adjacent to the direct …
Tokai, Japan has been upgraded. A 3He front detector was installed adjacent to the direct …
Neutron sources for large scale user facilities: The potential of high current accelerator-driven neutron sources
P Zakalek, T Gutberlet, T Brückel - Progress in Particle and Nuclear …, 2025 - Elsevier
A review of neutron sources for large scale user facilities is provided, aimed at users of
neutron sources who need to understand the characteristics and peculiarities of the different …
neutron sources who need to understand the characteristics and peculiarities of the different …
McStas (i): Introduction, use, and basic principles for ray-tracing simulations
We present an overview of, and an introduction to, the general-purpose neutron simulation
package McStas. We present the basic principles behind Monte Carlo ray-tracing …
package McStas. We present the basic principles behind Monte Carlo ray-tracing …
KWS-1 high-resolution small-angle neutron scattering instrument at JCNS: current state
AV Feoktystov, H Frielinghaus, Z Di… - Journal of applied …, 2015 - journals.iucr.org
The KWS-1 small-angle neutron scattering (SANS) instrument operated by the Jülich Centre
for Neutron Science (JCNS) at the research reactor FRM II of the Heinz Maier-Leibnitz …
for Neutron Science (JCNS) at the research reactor FRM II of the Heinz Maier-Leibnitz …
Physicochemical approach to understanding the structure, conformation, and activity of mannan polysaccharides
Extracellular polysaccharides are widely produced by bacteria, yeasts, and algae. These
polymers are involved in several biological functions, such as bacteria adhesion to surface …
polymers are involved in several biological functions, such as bacteria adhesion to surface …
Modern methods for studying polymer complexes in aqueous and organic solutions
This review summarizes published data concerning modern physicochemical methods used
to study complexation processes of polymers in solutions. Some of them—dynamic light …
to study complexation processes of polymers in solutions. Some of them—dynamic light …