CK2 and the Hallmarks of Cancer
MB Firnau, A Brieger - Biomedicines, 2022 - mdpi.com
Cancer is a leading cause of death worldwide. Casein kinase 2 (CK2) is commonly
dysregulated in cancer, impacting diverse molecular pathways. CK2 is a highly conserved …
dysregulated in cancer, impacting diverse molecular pathways. CK2 is a highly conserved …
Cancer Stem Cell and Aggressiveness Traits Are Promoted by Stable Endothelin-Converting Enzyme-1c in Glioblastoma Cells
Glioblastoma (GBM) is the most common and aggressive type of brain tumor due to its
elevated recurrence following treatments. This is mainly mediated by a subpopulation of …
elevated recurrence following treatments. This is mainly mediated by a subpopulation of …
Cisplatin-resistance and aggressiveness are enhanced by a highly stable endothelin-converting enzyme-1c in lung cancer cells
C Almarza, K Villalobos-Nova, MA Toro, M González… - Biological Research, 2024 - Springer
Background Lung cancer constitutes the leading cause of cancer mortality. High levels of
endothelin-1 (ET-1), its cognate receptor ETAR and its activating enzyme, the endothelin …
endothelin-1 (ET-1), its cognate receptor ETAR and its activating enzyme, the endothelin …
Target identification of usnic acid in bacterial and human cells
SA Ruddell, D Mostert, SA Sieber - RSC Chemical Biology, 2024 - pubs.rsc.org
Usnic acid is a natural product with versatile biological activities against various organisms.
Here, we utilise a chemical proteomic strategy to gain insights into its target scope in …
Here, we utilise a chemical proteomic strategy to gain insights into its target scope in …
The CK2/ECE1c Partnership: An Unveiled Pathway to Aggressiveness in Cancer
K Villalobos-Nova, MÁ Toro, P Pérez-Moreno… - Kinases and …, 2023 - mdpi.com
The endothelin-1 (ET1) peptide has a pathological role in the activation of proliferation,
survival and invasiveness pathways in different cancers. ET1's effects rely on its activation …
survival and invasiveness pathways in different cancers. ET1's effects rely on its activation …
Estudio in vitro del efecto de boldina y algunos derivados en la viabilidad de células de cáncer colorrectal
KE Villalobos Nova - 2022 - repositorio.uchile.cl
El cáncer colorrectal (CCR) es el segundo tipo de cáncer más mortal en el mundo,
estimándose que su incidencia aumentará en un 56% para 2040. El tratamiento tradicional …
estimándose que su incidencia aumentará en un 56% para 2040. El tratamiento tradicional …
Investigating the Potential Roles of Human (Endothelin convert enzyme-1) ECE-1 in Congenital Heart Diseases Using a Humanized Yeast System of Apoptosis
H **e - 2022 - figshare.le.ac.uk
CHDs (congenital heart diseases) are the most common birth defects that affects over 1% of
new-borns and there are approximately 30-50% of mortality caused by birth defects is due to …
new-borns and there are approximately 30-50% of mortality caused by birth defects is due to …
Computational Biology Dynamics of Mps1 Kinase Molecular Interactions with Isoflavones Reveals a Chemical Scaffold with Potential to Develop New Therapeutics for …
L Pugh, A Pancholi, PC Purat, S Agudo-Alvarez… - International Journal of …, 2022 - mdpi.com
The protein kinase Mps1 (monopolar spindle 1) is an important regulator of the Spindle
Assembly Checkpoint (SAC), the evolutionary conserved checkpoint system of higher …
Assembly Checkpoint (SAC), the evolutionary conserved checkpoint system of higher …