Recent advances in type-2-cell-mediated immunity: insights from helminth infection

NL Harris - Immunity, 2017 - cell.com
Type-2-cell-mediated immune responses play a critical role in mediating both host-
resistance and disease-tolerance mechanisms during helminth infections. Recently, type 2 …

Molecular testing for clinical diagnosis and epidemiological investigations of intestinal parasitic infections

JJ Verweij, CR Stensvold - Clinical microbiology reviews, 2014 - journals.asm.org
Over the past few decades, nucleic acid-based methods have been developed for the
diagnosis of intestinal parasitic infections. Advantages of nucleic acid-based methods are …

Three common assumptions about inflammation, aging, and health that are probably wrong

TW McDade - Proceedings of the National Academy of Sciences, 2023 - pnas.org
Chronic inflammation contributes to the onset and progression of cardiovascular disease
and other degenerative diseases of aging. But does it have to? This article considers the …

Regulation of host metabolic health by parasitic helminths

S Sikder, D Pierce, ER Sarkar, C McHugh… - Trends in …, 2024 - cell.com
Obesity is a worldwide pandemic and major risk factor for the development of metabolic
syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit …

Strongyloidiasis with emphasis on human infections and its different clinical forms

R Toledo, C Munoz-Antoli, JG Esteban - Advances in parasitology, 2015 - Elsevier
Strongyloidiasis (caused by Strongyloides stercoralis, and to a lesser extent by
Strongyloides fuelleborni) is one of the most neglected tropical diseases with endemic areas …

Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes

DR Pierce, M McDonald, L Merone, L Becker… - Nature …, 2023 - nature.com
The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic
parasitic worm infections suggests a protective role for worms against metabolic disorders …

Helminth infection protects against high fat diet-induced obesity via induction of alternatively activated macrophages

C Su, CY Chen, Y Li, SR Long, W Massey, DV Kumar… - Scientific reports, 2018 - nature.com
Epidemiological studies indicate an inverse correlation between the prevalence of the so-
called western diseases, such as obesity and metabolic syndrome, and the exposure to …

Infection with soil-transmitted helminths is associated with increased insulin sensitivity

AE Wiria, F Hamid, LJ Wammes, MA Prasetyani… - PloS one, 2015 - journals.plos.org
Objective Given that helminth infections have been shown to improve insulin sensitivity in
animal studies, which may be explained by beneficial effects on energy balance or by a shift …

Global issues in allergy and immunology: parasitic infections and allergy

AA Cruz, PJ Cooper, CA Figueiredo… - Journal of Allergy and …, 2017 - Elsevier
Allergic diseases are on the increase globally in parallel with a decrease in parasitic
infection. The inverse association between parasitic infections and allergy at an ecological …

Application of PCR-based methods for diagnosis of intestinal parasitic infections in the clinical laboratory

JJ Verweij - Parasitology, 2014 - cambridge.org
For many years PCR-and other DNA-based methods of pathogen detection have been
available in most clinical microbiology laboratories; however, until recently these tools were …