Implementing non-invasive prenatal testing in a national screening program: lessons learned from the TRIDENT studies

M Skojo, MI Srebniak, L Henneman… - Best Practice & …, 2024 - Elsevier
ABSTRACT The Dutch NIPT Consortium, a multidisciplinary collaboration of stakeholders in
prenatal care initiated and launched the TRIDENT studies. The goal of the TRIDENT studies …

Issues associated with possible implementation of Non‐Invasive Prenatal Testing (NIPT) in first‐tier screening: A rapid sco** review

M Ghiasi, C Armour, M Walker, N Shaver… - Prenatal …, 2023 - Wiley Online Library
In recent years, as the implementation and use of Non‐Invasive Prenatal Testing (NIPT)
have increased, the cost of the test has been decreasing. The cost of NIPT is expected to fall …

Non‐invasive cell‐free fetal DNA testing for aneuploidy: multicenter study of 31 515 singleton pregnancies in southeastern China

L Xu, H Huang, N Lin, Y Wang, D He… - … in Obstetrics & …, 2020 - Wiley Online Library
Objective To analyze the non‐invasive prenatal testing (NIPT) for aneuploidy results of 31
515 singleton pregnancies in Fujian province, southeastern China, and assess its …

[PDF][PDF] Non-invasive prenatal testing for everybody or contingent screening

KRM van der Meij, L Henneman… - Prenatal …, 2023 - researchgate.net
Objective: To compare the advantages and disadvantages of two main implementation
strategies for non-invasive prenatal testing (NIPT) for the detection of trisomies 21, 13 and …

Cost-effectiveness of prenatal screening and diagnostic strategies for Down syndrome: A microsimulation modeling analysis

W Zhang, T Mohammadi, J Sou, AH Anis - PLoS One, 2019 - journals.plos.org
Objectives Down syndrome (DS) is the most frequently occurring fetal chromosomal
abnormality and different prenatal screening strategies are used for determining risk of DS …

Fetal aneuploidy: screening and diagnostic testing

NM LeFevre, RL Sundermeyer - American Family Physician, 2020 - aafp.org
Aneuploidy is the presence of one or more extra chromosomes or the absence of one or
more chromosomes. The risk of fetal aneuploidy rises with increasing maternal age …

Introducing the non-invasive prenatal testing for detection of Down syndrome in China: a cost-effectiveness analysis

W Shang, Y Wan, J Chen, Y Du, J Huang - BMJ open, 2021 - bmjopen.bmj.com
Objective This study aimed to compare the health economic value of a non-invasive prenatal
testing (NIPT) strategy against a second-trimester triple screening (STS) strategy for the …

Clinical validation of a novel automated cell‐free DNA screening assay for trisomies 21, 13, and 18 in maternal plasma

O Ericsson, T Ahola, F Dahl, F Karlsson… - Prenatal …, 2019 - Wiley Online Library
Objective To evaluate clinical performance of a new automated cell‐free (cf) DNA assay in
maternal plasma screening for trisomies 21, 18, and 13, and to determine fetal sex. Method …

Should pregnant women be charged for non-invasive prenatal screening? Implications for reproductive autonomy and equal access

EM Bunnik, A Kater-Kuipers, RJH Galjaard… - Journal of Medical …, 2020 - jme.bmj.com
The introduction of non-invasive prenatal testing (NIPT) in healthcare systems around the
world offers an opportunity to reconsider funding policies for prenatal screening. In some …

Current controversies in prenatal diagnosis: Noninvasive prenatal testing should replace other screening strategies for fetal trisomies 13, 18, 21

P Pandya, B Levy, EA Sistermans - Prenatal Diagnosis, 2024 - Wiley Online Library
This is a written summary of the oral debate presented at the International Society for
Prenatal Diagnosis annual conference in Edinburgh in 2023. The topic under debate is …