Genomic risk factors for cervical cancer

D Ramachandran, T Dörk - Cancers, 2021 - mdpi.com
Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in
females worldwide. Despite an active immunisation strategy in many countries, high-risk …

The regulation of PBXs and their emerging role in cancer

Y Liu, X Ao, X Zhou, C Du… - Journal of Cellular and …, 2022 - Wiley Online Library
Pre‐B‐cell leukaemia transcription factor (PBX) proteins are a subfamily of evolutionarily
conserved, atypical homeodomain transcription factors that belong to the superfamily of …

In-silico analysis reveals Quinic acid as a multitargeted inhibitor against cervical cancer

S Ahmad, S Sayeed, N Bano, K Sheikh… - Journal of Biomolecular …, 2023 - Taylor & Francis
The cervix is the lowermost part of the uterus that connects to the vagina, and cervical
cancer is a malignant cervix tumour. One of this cancer's most important risk factors is HPV …

miRNAs as Interconnectors between Obesity and Cancer

GD González-Sánchez, AJ Granados-López… - Non-coding RNA, 2024 - mdpi.com
Obesity and cancer are a concern of global interest. It is proven that obesity may trigger the
development or progression of some types of cancer; however, the connection by non …

Methylation, Gene Expression, and Risk Genotypes at the TERTCLPTM1L Locus in Cervical Cancer

D Ramachandran, Q Mao, D Liao… - Molecular …, 2025 - Wiley Online Library
The reverse transcriptase subunit of telomerase, TERT, is frequently activated in high‐grade
dysplasia and invasive cancers of the uterine cervix. Telomerase activation through …

[HTML][HTML] Paired-box gene 8 (PAX8) and its association with epithelial carcinomas

K Khizer, J Padda, A Khedr, F Tasnim, OA Al-Ewaidat… - Cureus, 2021 - ncbi.nlm.nih.gov
Cancer is the second most common culprit of mortality in the United States and epithelial
carcinomas are considered as one of the most predominant types of cancer. The association …

Validation and functional follow‐up of cervical cancer risk variants at the HLA locus

R Eisenblätter, F Seifert, P Schürmann, T Beckhaus… - HLA, 2024 - Wiley Online Library
Cervical cancer is the fourth most common cancer in females. Genome‐wide association
studies (GWASs) have proposed cervical cancer susceptibility variants at the HLA locus on …

A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification

J Hu, S Wang, X Zhang, W Yan, H Liu, X Chen… - Archives of …, 2024 - Springer
Genetic variants can affect gene expression by altering the level of N6-methyladenosine
(m6A) modifications. A better understanding of the association of these genetic variants with …

Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer

D Ramachandran, J Dennis, L Fachal… - Human Molecular …, 2022 - academic.oup.com
Cervical cancer is among the leading causes of cancer-related death in females worldwide.
Infection by human papillomavirus (HPV) is an established risk factor for cancer …

[HTML][HTML] Association of two genomic variants with HPV type-specific risk of cervical cancer

F Seifert, R Eisenblätter, J Beckmann… - Tumour Virus …, 2023 - Elsevier
Problem Human papillomavirus infection is integral to develo** invasive cervical cancer in
the majority of patients. In a recent genome-wide association study, rs9357152 and …