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[HTML][HTML] Interaction between bone and immune cells: Implications for postmenopausal osteoporosis
Postmenopausal osteoporosis is a systemic disease characterized by the loss of bone mass
and increased bone fracture risk largely resulting from significantly reduced levels of the …
and increased bone fracture risk largely resulting from significantly reduced levels of the …
T-cell mediated inflammation in postmenopausal osteoporosis
Osteoporosis is the most prevalent metabolic bone disease that affects half the women in the
sixth and seventh decade of life. Osteoporosis is characterized by uncoupled bone …
sixth and seventh decade of life. Osteoporosis is characterized by uncoupled bone …
Physiological and pathophysiological bone turnover—role of the immune system
Osteoporosis develops when the rate of osteoclastic bone breakdown (resorption) exceeds
that of osteoblastic bone formation, which leads to loss of BMD and deterioration of bone …
that of osteoblastic bone formation, which leads to loss of BMD and deterioration of bone …
Time trends for risk of severe age-related diseases in individuals with and without HIV infection in Denmark: a nationwide population-based cohort study
LD Rasmussen, MT May, G Kronborg, CS Larsen… - The lancet HIV, 2015 - thelancet.com
Background Whether the reported high risk of age-related diseases in HIV-infected people is
caused by biological ageing or HIV-associated risk factors such as chronic immune …
caused by biological ageing or HIV-associated risk factors such as chronic immune …
The role of inflammatory cytokines, the RANKL/OPG axis, and the immunoskeletal interface in physiological bone turnover and osteoporosis
MN Weitzmann - Scientifica, 2013 - Wiley Online Library
Although it has long been recognized that inflammation, a consequence of immune‐driven
processes, significantly impacts bone turnover, the degree of centralization of skeletal and …
processes, significantly impacts bone turnover, the degree of centralization of skeletal and …
Changes in bone mineral density after initiation of antiretroviral treatment with tenofovir disoproxil fumarate/emtricitabine plus atazanavir/ritonavir, darunavir/ritonavir …
Background. Specific antiretroviral therapy (ART) medications and the severity of human
immunodeficiency virus (HIV) disease before treatment contribute to bone mineral density …
immunodeficiency virus (HIV) disease before treatment contribute to bone mineral density …
Contribution of viral and bacterial infections to senescence and immunosenescence
Cellular senescence is a key biological process characterized by irreversible cell cycle
arrest. The accumulation of senescent cells creates a pro-inflammatory environment that can …
arrest. The accumulation of senescent cells creates a pro-inflammatory environment that can …
Antiretroviral therapy induces a rapid increase in bone resorption that is positively associated with the magnitude of immune reconstitution in HIV infection
Objective: Antiretroviral therapy (ART) paradoxically intensifies bone loss in the setting of
HIV infection. Although the extent of bone loss varies, it occurs with virtually all ART types …
HIV infection. Although the extent of bone loss varies, it occurs with virtually all ART types …
Low Baseline CD4+ Count Is Associated With Greater Bone Mineral Density Loss After Antiretroviral Therapy Initiation
Background. Bone mineral density (BMD) decreases 2%–6% in the 2 years after
antiretroviral therapy (ART) initiation. Pre-ART immune deficiency and early immune …
antiretroviral therapy (ART) initiation. Pre-ART immune deficiency and early immune …
[PDF][PDF] Morbidity in older HIV-infected patients: impact of long-term antiretroviral use
G Guaraldi, M Prakash, C Moecklinghoff, HJ Stellbrink - Aids Rev, 2014 - researchgate.net
The introduction of HAART has represented a major advance in the care of people with HIV.
By markedly increasing life expectancy, HAART has significantly changed the pattern of HIV …
By markedly increasing life expectancy, HAART has significantly changed the pattern of HIV …