Hemorrhagic shock

JW Cannon - New England Journal of Medicine, 2018 - Mass Medical Soc
Hemorrhagic Shock | New England Journal of Medicine Skip to main content Access provided
byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine homepage …

Trauma-induced coagulopathy

EE Moore, HB Moore, LZ Kornblith, MD Neal… - Nature reviews Disease …, 2021 - nature.com
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

The European guideline on management of major bleeding and coagulopathy following trauma

DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Fibrinolysis shutdown correlation with thromboembolic events in severe COVID-19 infection

FL Wright, TO Vogler, EE Moore, HB Moore… - Journal of the American …, 2020 - Elsevier
Background COVID-19 predisposes patients to a prothrombotic state with demonstrated
microvascular involvement. The degree of hypercoagulability appears to correlate with …

Pulmonary angiopathy in severe COVID-19: physiologic, imaging, and hematologic observations

BV Patel, DJ Arachchillage, CA Ridge… - American journal of …, 2020 - atsjournals.org
Rationale: Clinical and epidemiologic data in coronavirus disease (COVID-19) have
accrued rapidly since the outbreak, but few address the underlying pathophysiology …

Advances in the understanding of trauma-induced coagulopathy

R Chang, JC Cardenas, CE Wade… - Blood, The Journal of …, 2016 - ashpublications.org
Ten percent of deaths worldwide are due to trauma, and it is the third most common cause of
death in the United States. Despite a profound upregulation in procoagulant mechanisms …

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

FCF Schmitt, V Manolov, J Morgenstern… - Annals of intensive …, 2019 - Springer
Background Septic coagulopathy represents a very dynamic disease entity, tilting from initial
hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt …

Acute traumatic coagulopathy: pathophysiology and resuscitation

JW Simmons, MF Powell - BJA: British Journal of Anaesthesia, 2016 - academic.oup.com
Acute Traumatic Coagulopathy occurs immediately after massive trauma when shock,
hypoperfusion, and vascular damage are present. Mechanisms for this acute coagulopathy …

Fibrinolysis shutdown in trauma: historical review and clinical implications

HB Moore, EE Moore, MD Neal… - Anesthesia & …, 2019 - journals.lww.com
Despite over a half-century of recognizing fibrinolytic abnormalities after trauma, we remain
in our infancy in understanding the underlying mechanisms causing these changes …

[HTML][HTML] Measuring fibrinolysis: from research to routine diagnostic assays

C Longstaff - Journal of Thrombosis and Haemostasis, 2018 - Elsevier
Development and standardization of fibrinolysis methods have progressed more slowly than
coagulation testing and routine high‐throughput screening tests for fibrinolysis are still …