HIV-associated neurocognitive disorder (HAND) is characterized by cognitive and
behavioral deficits in people living with HIV. HAND is still common in patients that take …

Astrocytes are the most abundant glial cells in the mammalian brain and directly participate
in the proper functioning of the nervous system by regulating ion homeostasis, controlling …

Lateral diffusion in the membrane and endosomal trafficking both contribute to the addition
and removal of AMPA receptors (AMPARs) at postsynaptic sites. However, the spatial …

Most of the excitatory synapses on principal neurons of the forebrain are located on
specialized structures called dendritic spines. Their morphology, comprising a spine head …

Adolescence is a transitional period from childhood to adulthood characterized by puberty
and brain maturation involving behavioral changes and environmental vulnerability. Diet is …

The Mercator projection map of the world provides a useful, but distorted, view of the relative
scale of countries. Current cellular models suffer from a similar distortion. Here, we …

Dendritic spines are small subcompartments that protrude from the dendrites of neurons and
are important for signaling activity and synaptic communication. These subcompartments …

Abnormalities in dendritic spines are manifestations of several neurodevelopmental and
psychiatric diseases. TAOK2 is one of the genes in the 16p11. 2 locus, copy number …

The ability of neurons to communicate and store information depends on the activity of
synapses which can be located on small protrusions (dendritic spines) or directly on the …

MicroRNAs are emerging as crucial regulators within the complex, dynamic environment of
the synapse, and they offer a promising new avenue for the treatment of neurological …