Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

The past several decades have witnessed great progress in “smart drug delivery”, an
advance technology that can deliver genes or drugs into specific locations of patients' body …

The blood–brain barrier (BBB) presents a significant obstacle for the treatment of many
central nervous system (CNS) disorders, including invasive brain tumors, Alzheimer's …

Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

The resonance behaviors of a few lipid-coated microbubbles acoustically activated in
viscoelastic media were comprehensively examined via radius response analysis. The size …

SonoVue microbubbles could serve as artificial nuclei for ultrasound-triggered stable and
inertial cavitation, resulting in beneficial biological effects for future therapeutic applications …

To improve therapeutic efficacy of nanocarrier drug delivery systems, it is essential to
improve their uptake and penetration in tumour tissue, enhance cellular uptake and ensure …

Traditional drug delivery systems, where pharmaceutical agents are conveyed to the target
tissue through the blood circulation, suffer of poor therapeutic efficiency and limited …

In biomedical research, ultrasonic cavitation, especially inertial cavitation (IC) has attracted
extensive attentions due to its ability to induce mechanical, chemical and thermal effects …

Encapsulated microbubbles combined with ultrasound have been widely utilized in various
biomedical applications; however, the bubble dynamics in viscoelastic medium have not …