Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
Despite the increasing number of GPCR structures and recent advances in peptide design,
the development of efficient technologies allowing rational design of high-affinity peptide …
the development of efficient technologies allowing rational design of high-affinity peptide …
Mind the gap—deciphering GPCR pharmacology using 3D pharmacophores and artificial intelligence
T Noonan, K Denzinger, V Talagayev, Y Chen, K Puls… - Pharmaceuticals, 2022 - mdpi.com
G protein-coupled receptors (GPCRs) are amongst the most pharmaceutically relevant and
well-studied protein targets, yet unanswered questions in the field leave significant gaps in …
well-studied protein targets, yet unanswered questions in the field leave significant gaps in …
Recent Advances in the Synthesis and Applications of m-Aryloxy Phenols
Since phenol derivatives have high potential as building blocks for the synthesis of bioactive
natural products and conducting polymers, many synthesis methods have been invented. In …
natural products and conducting polymers, many synthesis methods have been invented. In …
Multi-level biological network analysis and drug repurposing based on leukocyte transcriptomics in severe COVID-19: in silico systems biology to precision medicine
P Sagulkoo, H Chuntakaruk, T Rungrotmongkol… - Journal of personalized …, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic causes many morbidity and mortality
cases. Despite several developed vaccines and antiviral therapies, some patients …
cases. Despite several developed vaccines and antiviral therapies, some patients …
Identificación de posibles dianas terapéuticas en Alzheimer utilizando pipeline bioinformático combinado para aplicarlas al diseño de fármacos asistidos por …
LL Barriga Sanchez - 2023 - repositorio.uta.edu.ec
El acoplamiento molecular demostró que Estradiol y Tricostatina A pueden generar una
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
[ЦИТИРОВАНИЕ][C] Magic™ In Vitro Cell-based Opioid Receptor Functional Assay Service
WDOR Matter