A comprehensive review on process and engineering aspects of pharmaceutical wet granulation

P Suresh, I Sreedhar, R Vaidhiswaran… - Chemical Engineering …, 2017 - Elsevier
Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

Challenges in the simulation of drying in fluid bed granulation

M Askarishahi, MS Salehi, S Radl - Processes, 2023 - mdpi.com
Fluid bed granulation is faced with a high level of complexity due to the simultaneous
occurrence of agglomeration, breakage, and drying. These complexities should be …

A novel process for coating of silica aerogel microspheres for controlled drug release applications

M Alnaief, S Antonyuk, CM Hentzschel… - Microporous and …, 2012 - Elsevier
Aerogels are nanoporous materials with an open-pore structure and high specific surface
area. Because of their outstanding properties they have been investigated in immense fields …

[HTML][HTML] Ethanolamine-modified zeolite–Chitosan beads as new adsorbents for carbon dioxide capture and crystal violet removal

NM Thuan, NTM Linh, NTT Phuong, NTH Duong… - Case Studies in …, 2024 - Elsevier
This study examined the synthesis of an amine-impregnated bead with high content of
zeolite X using chitosan as a binding agent. XRD analysis was conducted confirming the …

CFD–DEM simulation of fine particles in a spouted bed apparatus with a Wurster tube

P Breuninger, D Weis, I Behrendt, P Grohn, F Krull… - Particuology, 2019 - Elsevier
In this work, a coupled computational fluid dynamics–discrete element method (CFD–DEM)
approach was employed to evaluate the spouting behavior of fine, cohesive powders in a …

Influence of drying conditions on layer porosity in fluidized bed spray granulation

C Rieck, T Hoffmann, A Bück, M Peglow, E Tsotsas - Powder Technology, 2015 - Elsevier
Particle coating experiments were performed in a lab-scale fluidized bed with varying
process parameters, such as spraying rate and air inlet temperature, leading to different …

Continuous pellet coating in a Wurster fluidized bed process

N Hampel, A Bück, M Peglow, E Tsotsas - Chemical engineering science, 2013 - Elsevier
Coating of particles in fluidized beds is a widely spread technique to generate well defined
properties of the dispersed solids or to protect active ingredients. The majority of coating …

Color-PTV measurement and CFD-DEM simulation of the dynamics of poly-disperse particle systems in a pseudo-2D fluidized bed

Z Jiang, T Hagemeier, A Bück, E Tsotsas - Chemical Engineering Science, 2018 - Elsevier
In a pseudo-2D fluidized bed, a new color particle tracking velocimetry (PTV) method,
integrating the Voronoi tracking algorithm and the relaxation probability tracking algorithm, is …

[HTML][HTML] Sha** technical catalyst particles in a bottom-spray fluidized bed

AM Alkadhem, HO Mohamed, SR Kulkarni… - Powder Technology, 2024 - Elsevier
This work aims to elucidate the particle growth mechanism during agglomeration using a
bottom-spray fluidized bed process to produce technical catalysts. The influences of the …

Characterization of the internal morphology of agglomerates produced in a spray fluidized bed by X-ray tomography

M Dadkhah, M Peglow, E Tsotsas - Powder Technology, 2012 - Elsevier
The internal structure of granules produced by spray fluidized bed agglomeration was
investigated by means of X-ray micro-computer-tomography. The X-ray tomography delivers …