Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

In India, increasing lifespan and decreasing fertility rates have resulted in a growing number
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …

The aim was to explore the self-reported impact of the COVID-19 pandemic on nutrition and
physical activity behaviour in Dutch older adults and to identify subgroups most susceptible …

Background The aim was to investigate the associations of sarcopenia as defined by
European Working Group on Sarcopenia in Older People (EWGSOP) and Foundation for the …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and
together with polygenetic risk stratification can contribute towards planning of feasible and …

Obesity is an emerging condition, with a prevalence of~ 20%. Although the simple
measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and …

BACKGROUND/OBJECTIVES Frailty, loneliness, and social isolation are all associated with
adverse outcomes in older adults, but little is known about their combined impact on …

Objective Competing events are often ignored in epidemiological studies. Conventional
methods for the analysis of survival data assume independent or noninformative censoring …

Low muscle strength is an important heritable indicator of poor health linked to morbidity and
mortality in older people. In a genome-wide association study meta-analysis of 256,523 …