Fibrillarin (FBL) is a highly conserved and well-researched nucleolar protein found in
eukaryotes. Its presence was first identified in 1985 through protein immunoblotting …

Organelles are responsible for biochemical and cellular processes that sustain life and their
dysfunction causes diseases from cancer to neurodegeneration. While researchers are …

Studies of the regulation of nucleolar function are critical for ascertaining clearer insights into
the basic biological underpinnings of ribosome biogenesis (RB), and for future development …

RNA provides the framework for the assembly of some of the most intricate macromolecular
complexes within the cell, including the spliceosome and the mature ribosome. The …

The retinoid cycle is a metabolic process in the vertebrate retina that continuously
regenerates 11-cis-retinal (11-cisRAL) from the all-trans-retinal (atRAL) isomer. atRAL …

Background Primary cilia are sensory organelles crucial for organ development. The pivotal
structure of the primary cilia is a microtubule that is generated via tubulin polymerization …

As a transcription factor, NR2F1 regulates spatiotemporal gene expression during
development and in adulthood. Aberrant NR2F1 causes a rare neurodevelopmental …

Ribosome biogenesis is the essential process that all living organisms need to produce the
protein synthesizing machinery within cells. It has become apparent in recent years that …

Ribosomes are the complex macromolecular machines which assemble proteins in all forms
of life, and their production process is known as ribosome biogenesis (RB). In eukaryotes …

RNA provides the framework for the assembly of some of the most intricate macromolecular
complexes within the cell, including the spliceosome and the mature ribosome. The …