[HTML][HTML] Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids
R Pluta, B Miziak, SJ Czuczwar - Molecules, 2023 - mdpi.com
Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …
disability, dementia, and mortality, which is a global problem. These phenomena are …
[HTML][HTML] Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats
The present study is aimed to determine the efficacy and dose response of the nuciferine (1),
norcoclaurine (2) and crude extract of Nelumbo nucifera in managements of diabetes …
norcoclaurine (2) and crude extract of Nelumbo nucifera in managements of diabetes …
[HTML][HTML] Synthesis and investigation of the analgesic potential of enantiomerically pure schiff bases: a mechanistic approach
Schiff bases are a class of organic compounds with azomethine moiety, exhibiting a wide
range of biological potentials. In this research, six chiral Schiff bases, three 'S'series (H1 …
range of biological potentials. In this research, six chiral Schiff bases, three 'S'series (H1 …
Alleviative effect of scopolamine‑induced memory deficit via enhancing antioxidant and cholinergic function in rats by pinostrobin from Boesenbergia rotunda (L.)
Pinostrobin, a key bioactive compound found in the medicinal plant Boesenbergia rotunda
(L.), has been noted for its beneficial biological properties including antioxidant, anti …
(L.), has been noted for its beneficial biological properties including antioxidant, anti …
[HTML][HTML] Synthetic mono-carbonyl curcumin analogues attenuate oxidative stress in mouse models
Alzheimer's disease is the commonest form of dementia associated with short-term memory
loss and impaired cognition and, worldwide, it is a growing health issue. A number of …
loss and impaired cognition and, worldwide, it is a growing health issue. A number of …
[HTML][HTML] The antitumour activity of a curcumin and piperine loaded irgd-modified liposome: in vitro and in vivo evaluation
Y Wang, X Huang, H Chen, Q Wu, Q Zhao, D Fu, Q Liu… - Molecules, 2023 - mdpi.com
Lung cancer is one of the most common cancers around the world, with a high mortality rate.
Despite substantial advancements in diagnoses and therapies, the outlook and survival of …
Despite substantial advancements in diagnoses and therapies, the outlook and survival of …
[HTML][HTML] Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition
T Tuzimski, A Petruczynik, M Szultka-Młyńska… - Molecules, 2022 - mdpi.com
An important strategy for treating neurodegenerative disorders is to maintain the levels of
acetylcholine in the synaptic cleft by blocking the cholinesterases. Searching for new …
acetylcholine in the synaptic cleft by blocking the cholinesterases. Searching for new …
SwissADME studies and Density Functional Theory (DFT) approaches of methyl substituted curcumin derivatives
MB Afridi, H Sardar, G Serdaroğlu, SWA Shah… - … Biology and Chemistry, 2024 - Elsevier
Research suggests curcumin's safety and efficacy, prompting interest in its use for treating
and preventing various human diseases. The current study aimed to predict drag ability of …
and preventing various human diseases. The current study aimed to predict drag ability of …
[HTML][HTML] Cholinesterases inhibition, anticancer and antioxidant activity of novel benzoxazole and naphthoxazole analogs
A Skrzypek, M Karpińska, M Juszczak, A Grabarska… - Molecules, 2022 - mdpi.com
Benzoxazole and naphthoxazole fused systems are found in many biologically active
molecules. Novel benzoxazole and naphthoxazole analogs functionalized by the 2, 4 …
molecules. Novel benzoxazole and naphthoxazole analogs functionalized by the 2, 4 …
[HTML][HTML] Investigation of antistress and antidepressant activities of synthetic curcumin analogues: Behavioral and biomarker approach
Depression is a serious psychiatric disorder that affects millions of individuals all over the
world, thus demanding special attention from researchers in order to investigate its effective …
world, thus demanding special attention from researchers in order to investigate its effective …