[HTML][HTML] Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids

R Pluta, B Miziak, SJ Czuczwar - Molecules, 2023 - mdpi.com
Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …

[HTML][HTML] Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats

S Khan, HU Khan, FA Khan, A Shah, A Wadood… - Pharmaceuticals, 2022 - mdpi.com
The present study is aimed to determine the efficacy and dose response of the nuciferine (1),
norcoclaurine (2) and crude extract of Nelumbo nucifera in managements of diabetes …

[HTML][HTML] Synthesis and investigation of the analgesic potential of enantiomerically pure schiff bases: a mechanistic approach

HH Afridi, M Shoaib, FA Al-Joufi, SWA Shah, H Hussain… - Molecules, 2022 - mdpi.com
Schiff bases are a class of organic compounds with azomethine moiety, exhibiting a wide
range of biological potentials. In this research, six chiral Schiff bases, three 'S'series (H1 …

Alleviative effect of scopolamine‑induced memory deficit via enhancing antioxidant and cholinergic function in rats by pinostrobin from Boesenbergia rotunda (L.)

S Thongrong, T Promsrisuk, N Sriraksa… - Biomedical …, 2024 - spandidos-publications.com
Pinostrobin, a key bioactive compound found in the medicinal plant Boesenbergia rotunda
(L.), has been noted for its beneficial biological properties including antioxidant, anti …

[HTML][HTML] Synthetic mono-carbonyl curcumin analogues attenuate oxidative stress in mouse models

H Hussain, S Ahmad, SWA Shah, A Ullah, SU Rahman… - Biomedicines, 2022 - mdpi.com
Alzheimer's disease is the commonest form of dementia associated with short-term memory
loss and impaired cognition and, worldwide, it is a growing health issue. A number of …

[HTML][HTML] The antitumour activity of a curcumin and piperine loaded irgd-modified liposome: in vitro and in vivo evaluation

Y Wang, X Huang, H Chen, Q Wu, Q Zhao, D Fu, Q Liu… - Molecules, 2023 - mdpi.com
Lung cancer is one of the most common cancers around the world, with a high mortality rate.
Despite substantial advancements in diagnoses and therapies, the outlook and survival of …

[HTML][HTML] Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition

T Tuzimski, A Petruczynik, M Szultka-Młyńska… - Molecules, 2022 - mdpi.com
An important strategy for treating neurodegenerative disorders is to maintain the levels of
acetylcholine in the synaptic cleft by blocking the cholinesterases. Searching for new …

SwissADME studies and Density Functional Theory (DFT) approaches of methyl substituted curcumin derivatives

MB Afridi, H Sardar, G Serdaroğlu, SWA Shah… - … Biology and Chemistry, 2024 - Elsevier
Research suggests curcumin's safety and efficacy, prompting interest in its use for treating
and preventing various human diseases. The current study aimed to predict drag ability of …

[HTML][HTML] Cholinesterases inhibition, anticancer and antioxidant activity of novel benzoxazole and naphthoxazole analogs

A Skrzypek, M Karpińska, M Juszczak, A Grabarska… - Molecules, 2022 - mdpi.com
Benzoxazole and naphthoxazole fused systems are found in many biologically active
molecules. Novel benzoxazole and naphthoxazole analogs functionalized by the 2, 4 …

[HTML][HTML] Investigation of antistress and antidepressant activities of synthetic curcumin analogues: Behavioral and biomarker approach

H Hussain, S Ahmad, SWA Shah, A Ullah… - Biomedicines, 2022 - mdpi.com
Depression is a serious psychiatric disorder that affects millions of individuals all over the
world, thus demanding special attention from researchers in order to investigate its effective …