Management of keratoconus: an updated review

R Deshmukh, ZZ Ong, R Rampat… - Frontiers in …, 2023 - frontiersin.org
Keratoconus is the most common corneal ectatic disorder. It is characterized by progressive
corneal thinning with resultant irregular astigmatism and myopia. Its prevalence has been …

A review of keratoconus: diagnosis, pathophysiology, and genetics

VM Tur, C MacGregor, R Jayaswal, D O'Brart… - Survey of …, 2017 - Elsevier
We discuss new approaches to the early detection of keratoconus and recent investigations
regarding the nature of its pathophysiology. We review the current evidence for its complex …

Primary open-angle glaucoma preferred practice pattern®

SJ Gedde, K Vinod, MM Wright, KW Muir, JT Lind… - Ophthalmology, 2021 - Elsevier
Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …

[PDF][PDF] Primary open-angle glaucoma preferred practice pattern® guidelines

BE Prum, LF Rosenberg, SJ Gedde, SL Mansberger… - …, 2016 - academia.edu
Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy in adults
in which there is a characteristic acquired atrophy of the optic nerve and loss of retinal …

The genetic and environmental factors for keratoconus

A Gordon-Shaag, M Millodot… - BioMed research …, 2015 - Wiley Online Library
Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone‐
shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It …

Identifying causal variants at loci with multiple signals of association

F Hormozdiari, E Kostem, EY Kang… - Proceedings of the 5th …, 2014 - dl.acm.org
Although genome-wide association studies have successfully identified thousands of risk
loci for complex traits, only a handful of the biologically causal variants, responsible for …

The pathogenesis of keratoconus

AE Davidson, S Hayes, AJ Hardcastle, SJ Tuft - Eye, 2014 - nature.com
Keratoconus (KC) is a common degenerative condition that frequently results in visual loss
with an onset typically in early adulthood. It is the single most common reason for …

The keratoconus enigma: a review with emphasis on pathogenesis

G Ferrari, P Rama - The ocular surface, 2020 - Elsevier
Purpose To review the literature on the etiopathogenesis of keratoconus (KC). Methods A
literature search was conducted using PUBMED and Google Scholar for keratoconus. The …

Biomechanical characterization of keratoconus corneas ex vivo with Brillouin microscopy

G Scarcelli, S Besner, R Pineda… - … ophthalmology & visual …, 2014 - iovs.arvojournals.org
Purpose.: Loss of corneal strength is a central feature of keratoconus progression. However,
it is currently difficult to measure corneal mechanical changes noninvasively. The objective …

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

PG Hysi, CY Cheng, H Springelkamp, S Macgregor… - Nature …, 2014 - nature.com
Elevated intraocular pressure (IOP) is an important risk factor in develo** glaucoma, and
variability in IOP might herald glaucomatous development or progression. We report the …