Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review

T Teka, L Zhang, X Ge, Y Li, L Han, X Yan - Phytochemistry, 2022 - Elsevier
Stilbenes are some of the important phenolic compounds originating from plant families like
Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6 …

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

K Nepali, S Sharma, M Sharma, PMS Bedi… - European journal of …, 2014 - Elsevier
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Biological effects of resveratrol

L Frémont - Life sciences, 2000 - Elsevier
Resveratrol (3, 4′, 5 trihydroxystilbene) is a naturally occuring phytoalexin produced by
some spermatophytes, such as grapevines, in response to injury. Given that it is present in …

Resveratrol in medicinal chemistry: a critical review of its pharmacokinetics, drug-delivery, and membrane interactions

A R. Neves, M Lucio, J LC Lima… - Current medicinal …, 2012 - benthamdirect.com
Resveratrol is a polyphenol that among other sources occurs in grapes and for this reason,
red wines also contain considerable amounts of this compound. Resveratrol is thought to be …

Cardiovascular protective effects of resveratrol

S Bradamante, L Barenghi… - Cardiovascular drug …, 2004 - Wiley Online Library
ABSTRACT Resveratrol (3, 4′, 5‐trihydroxy‐trans‐stilbene), a phytoalexin found in grape
skins, peanuts, and red wine, has been reported to have a wide range of biological and …

[PDF][PDF] Resveratrol: from grapevines to mammalian biology.

S Pervaiz - Faseb Journal, 2003 - researchgate.net
With the rapid advances made over the last two decades in biomedical research, there has
been an unprecedented interest in unraveling the magical properties of some commonly …

Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad?

P Saiko, A Szakmary, W Jaeger, T Szekeres - Mutation Research/Reviews …, 2008 - Elsevier
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene; RV), a dietary constituent found in grapes
and wine, exerts a wide variety of pharmacological activities. Because the grape skins are …

Isoflavones, lignans and stilbenes–origins, metabolism and potential importance to human health

A Cassidy, B Hanley… - Journal of the Science …, 2000 - Wiley Online Library
Interest in the physiological role of the bioactive compounds present in plants has increased
dramatically over the last decade. Of particular interest in relation to human health are the …

Dose-dependency of resveratrol in providing health benefits

S Mukherjee, JI Dudley, DK Das - Dose-response, 2010 - journals.sagepub.com
This review describes the dose-dependent health benefits of resveratrol, a polyphenolic
antioxidant that is found in a variety of foods, especially grape skin and red wine …

Piceid, the major resveratrol derivative in grape juices

AI Romero-Pérez, M Ibern-Gómez… - Journal of agricultural …, 1999 - ACS Publications
The levels of trans-piceid, cis-piceid, trans-resveratrol, and cis-resveratrol have been
measured in 36 grape juices using an HPLC system with spectral analysis of eluting peaks …