Simple Summary Diet can influence human health in both positive and negative ways. Ω-3
polyunsaturated fatty acids have an overall positive effect on humans. The sources of these …

Ferroptosis is a recently discovered distinct type of regulated cell death caused by the
accumulation of lipid-based ROS. Metabolism and expression of specific genes affect the …

Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Traditional chemotherapy relies on the premise that rapidly proliferating cancer cells are
more likely to be killed by a cytotoxic agent, but in reality, the long-standing problem of …

Over the past decades, extensive studies have addressed the therapeutic effects of omega-3
polyunsaturated fatty acids (omega-3 FAs) against different human diseases such as …

Abstract n-3 polyunsaturated fatty acids (PUFA) have been shown in many clinical studies to
attenuate inflammatory responses. Although inflammatory responses are orchestrated by a …

The complexity of cancer biology and its clinical manifestation are driven by genetic,
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …

Background The activity of P-glycoprotein (Pgp) and multidrug resistance related protein 1
(MRP1), two membrane transporters involved in multidrug resistance of colon cancer, is …

Ephrin type-A receptor 2 (EphA2), a receptor tyrosine kinase, is overexpressed in human
breast cancers often linked to poor patient prognosis. Accumulating evidence demonstrates …

Docosahexaenoic acid (DHA) is important for brain function, and higher DHA intake is
inversely correlated with relative risk of Alzheimer's disease. The potential benefits of DHA …