2024 ESC guidelines for the management of chronic coronary syndromes: developed by the task force for the management of chronic coronary syndromes of the …

C Vrints, F Andreotti, KC Koskinas… - European heart …, 2024‏ - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Coronary microvascular dysfunction: mechanisms and functional assessment

PG Camici, G d'Amati, O Rimoldi - Nature Reviews Cardiology, 2015‏ - nature.com
Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test …

J Knuuti, H Ballo, LE Juarez-Orozco… - European heart …, 2018‏ - academic.oup.com
Aims To determine the ranges of pre-test probability (PTP) of coronary artery disease (CAD)
in which stress electrocardiogram (ECG), stress echocardiography, coronary computed …

A machine-learning approach for computation of fractional flow reserve from coronary computed tomography

L Itu, S Rapaka, T Passerini… - Journal of applied …, 2016‏ - journals.physiology.org
Fractional flow reserve (FFR) is a functional index quantifying the severity of coronary artery
lesions and is clinically obtained using an invasive, catheter-based measurement. Recently …

Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need

TJ Ford, D Corcoran, C Berry - Heart, 2018‏ - heart.bmj.com
The diagnostic management of patients with angina pectoris typically centres on the
detection of obstructive epicardial CAD, which aligns with evidence-based treatment options …

Physiological basis and long-term clinical outcome of discordance between fractional flow reserve and coronary flow velocity reserve in coronary stenoses of …

TP Van De Hoef, MA van Lavieren… - Circulation …, 2014‏ - ahajournals.org
Background—Discordance between fractional flow reserve (FFR) and coronary flow velocity
reserve (CFVR) may reflect important coronary pathophysiology but usually remains …

The evolving future of instantaneous wave-free ratio and fractional flow reserve

M Götberg, CM Cook, S Sen, S Nijjer, J Escaned… - Journal of the American …, 2017‏ - jacc.org
In this review, the authors reflect upon the role of coronary physiology in the modern
management of coronary artery disease. They critically appraise the scientific background of …

Coronary arterial function and disease in women with no obstructive coronary arteries

HR Reynolds, CN Bairey Merz, C Berry… - Circulation …, 2022‏ - ahajournals.org
Ischemic heart disease (IHD) is the leading cause of mortality in women. While traditional
cardiovascular risk factors play an important role in the development of IHD in women …

Is discordance of coronary flow reserve and fractional flow reserve due to methodology or clinically relevant coronary pathophysiology?

NP Johnson, RL Kirkeeide, KL Gould - JACC: Cardiovascular Imaging, 2012‏ - jacc.org
Objectives: The purpose of this study was to determine whether observed discordance
between coronary flow reserve (CFR) and fractional flow reserve (FFR) is due to …

Diagnostic classification of the instantaneous wave-free ratio is equivalent to fractional flow reserve and is not improved with adenosine administration: results of …

S Sen, KN Asrress, S Nijjer, R Petraco, IS Malik… - Journal of the American …, 2013‏ - jacc.org
Objectives: This study sought to determine if adenosine administration is required for the
pressure-only assessment of coronary stenoses. Background: The instantaneous wave-free …