Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention

D Capodanno, R Mehran, M Valgimigli… - Nature Reviews …, 2018 - nature.com
In patients with manifestations of cardiovascular disease, acetylsalicylic acid (popularly
known as aspirin) has been the mainstay of treatment for decades owing to its capacity to …

Predictors of stent thrombosis and their implications for clinical practice

T Gori, A Polimeni, C Indolfi, L Räber… - Nature Reviews …, 2019 - nature.com
Stent thrombosis (ST) is a rare but severe complication of coronary procedures with high
mortality, high relapse rate and a very complex pathophysiology. An individual's …

Dabigatran dual therapy with ticagrelor or clopidogrel after percutaneous coronary intervention in atrial fibrillation patients with or without acute coronary syndrome: a …

J Oldgren, PG Steg, SH Hohnloser… - European Heart …, 2019 - academic.oup.com
Aims After percutaneous coronary intervention (PCI) in patients with atrial fibrillation, safety
and efficacy with dabigatran dual therapy were evaluated in pre-specified subgroups of …

Treatment effects in randomized and nonrandomized studies of pharmacological interventions: a meta-analysis

M Salcher-Konrad, M Nguyen, J Savović… - JAMA network …, 2024 - jamanetwork.com
Importance Randomized clinical trials (RCTs) are widely regarded as the methodological
benchmark for assessing clinical efficacy and safety of health interventions. There is growing …

[HTML][HTML] Dual anticoagulant/antiplatelet activity of polyphenolic grape seeds extract

M Bijak, A Sut, A Kosiorek, J Saluk-Bijak, J Golanski - Nutrients, 2019 - mdpi.com
Because of the side-effects of commonly used anti-platelet and anticoagulant drugs,
investigations into plant substances with similar activities are very common. Based on our …

Development of a novel Apigenin dosage form as a substitute for the modern triple antithrombotic regimen

AD Tsiailanis, CC Tellis, P Papakyriakopoulou… - Molecules, 2023 - mdpi.com
The simultaneous administration of three antiplatelet agents has been proposed as an
efficient strategy for the secondary prevention of atherothrombotic events and is included in …

[HTML][HTML] Screening for the antiplatelet aggregation quality markers of Salvia yunnanensis based on an integrated approach

Y Li, Y Zhang, B Cao, F Zhang, M Niu, X Bai… - … of Pharmaceutical and …, 2020 - Elsevier
This study aimed to identify the antiplatelet aggregation quality markers of Salvia
yunnanensis (SY) based on an integrated approach. The effects of SY methanol extracts on …

Direct oral anticoagulants versus standard triple therapy in atrial fibrillation and PCI: meta-analysis

ND Brunetti, N Tarantino, L De Gennaro… - Open …, 2018 - openheart.bmj.com
The coexistence of coronary artery disease and atrial fibrillation (AF) in the same individuals
raises great concern about the co-treatment with different antithrombotic agents in the case …