Covering: 1997 to 2023 The shikimate pathway is the metabolic process responsible for the
biosynthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Seven …

Chorismate and isochorismate represent an important branching point connecting primary
and secondary metabolism in bacteria, fungi, archaea and plants. Chorismate-and …

Glycosylated polyene macrolides include effective antifungal agents, such as pimaricin,
nystatin, candicidin, and amphotericin B. For the treatment of systemic mycoses …

The long and successful history of isotopic labeling experiments within natural products
research has both changed and deepened our understanding of biosynthesis. As …

Muconic acid is a platform chemical and an important intermediate in the degradation
process of a series of aromatic compounds. Herein, a plasmid-free synthetic pathway in …

Neoantimycins are anticancer compounds of 15-membered ring antimycin-type
depsipeptides. They are biosynthesized by a hybrid multimodular protein complex of …

MqnA is the first enzyme on the futalosine pathway to menaquinone, which catalyzes the
dehydration of chorismate to yield 3-enolpyruvyl-benzoate (3-EPB). MqnA is also the only …

Chorismatase is an important enzyme involved in Shikimate pathway, which catalyzes the
conversion of chorismate into pyruvate and (dihydro)‐benzoic acid derivatives. According to …

Chorismatases catalyse the cleavage of chorismate, yielding (dihydroxy-) benzoate
derivatives, which often constitute starter units for pharmaceutically relevant secondary …

Chevalinulin A is a novel compound obtained from fungal strain Aspergillus chevalieri
isolated from deep sea cold seeps in 2022. Based on structural characterizations, the …