Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …

Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins
known as fusogens are responsible for mediating membrane fusion. However, until recently …

Apical extracellular matrices (aECMs) coat the exposed surfaces of animal bodies to shape
tissues, influence social interactions, and protect against pathogens and other …

During morphogenesis of the Caenorhabditis elegans embryo, hypodermal (or epidermal)
cells migrate to enclose the embryo in an epithelium and, subsequently, change shape …

In biomembrane fusion pathways, membranes are destabilized through insertions of
amphipathic protein segments, lipid reorganization via hemifusion, protein restructuring, and …

▪ Abstract Significant progress has been made in elucidating the mechanisms of viral
membrane fusion proteins; both those that function at low, as well as those that function at …

The polarized nature of epithelial cells is manifested by the nonrandom partitioning of
organelles within the cells, the concentration of intercellular junctions at one pole, and the …

Netrins are laminin-related proteins that guide circumferential migrations on the ectoderm.
To understand how netrin cues direct cell movements, we examined the expression of …

The function of epithelial cell sheets depends on the integrity of specialized cell–cell
junctions that connect neighbouring cells. We have characterized the novel coiled-coil …

Cell–cell fusion is a highly regulated and dramatic cellular event that is required for
development and homeostasis. Fusion may also play a role in the development of cancer …