Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …

Learning is primarily mediated by activity-dependent modifications of synaptic strength
within neuronal circuits. We discovered that place fields in hippocampal area CA1 are …

Dendritic calcium signaling is central to neural plasticity mechanisms that allow animals to
adapt to the environment. Intracellular calcium release (ICR) from the endoplasmic reticulum …

We often assume that the variables of functional and structural brain parameters—such as
synaptic weights, the firing rates of individual neurons, the synchronous discharge of neural …

Theories on the functions of the hippocampal system are based largely on two fundamental
discoveries: the amnestic consequences of removing the hippocampus and associated …

Clarifying gene expression in narrowly defined neuronal populations can provide insight
into cellular identity, computation, and functionality. Here, we used next-generation RNA …

Working memory is a fundamental feature of biological brains for perception, cognition, and
learning. In addition, learning with working memory, which has been show in conventional …

The hippocampal dentate gyrus is often viewed as a segregator of upstream information.
Physiological support for such function has been hampered by a lack of well-defined …

Theta-gamma phase coupling and spike timing within theta oscillations are prominent
features of the hippocampus and are often related to navigation and memory. However, the …