Adding the third dimension to virus life cycles: three-dimensional reconstruction of icosahedral viruses from cryo-electron micrographs
TS Baker, NH Olson, SD Fuller - Microbiology and Molecular …, 1999 - Am Soc Microbiol
Viruses are cellular parasites. The linkage between viral and host functions makes the study
of a viral life cycle an important key to cellular functions. A deeper understanding of many …
of a viral life cycle an important key to cellular functions. A deeper understanding of many …
Occupancy and mechanism in antibody-mediated neutralization of animal viruses
Neutralization of virus infectivity by antibodies is an important component of immunity to
several virus infections. Here, the immunochemical basis for the action of neutralizing …
several virus infections. Here, the immunochemical basis for the action of neutralizing …
Foot-and-mouth disease virus
E Domingo, E Baranowski, C Escarmı́s… - … and infectious diseases, 2002 - Elsevier
Foot-and-mouth disease virus (FMDV) is an aphthovirus of the family Picornaviridae and the
etiological agent of the economically most important animal disease. As a typical …
etiological agent of the economically most important animal disease. As a typical …
Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future
As a discipline, structural biology has been transformed by the three-dimensional electron
microscopy (3DEM)“Resolution Revolution” made possible by convergence of robust cryo …
microscopy (3DEM)“Resolution Revolution” made possible by convergence of robust cryo …
Structure and receptor binding
The causative agent of foot-and-mouth disease was first identified as a virus by Loeffler and
Frosch (1897)(see Brown, this volume), but visualisation of its general morphology was not …
Frosch (1897)(see Brown, this volume), but visualisation of its general morphology was not …
Cell recognition by foot-and-mouth disease virus that lacks the RGD integrin-binding motif: flexibility in aphthovirus receptor usage
Cell surface molecules that can act as virus receptors may exert an important selective
pressure on RNA viral quasispecies. Large population passages of foot-and-mouth disease …
pressure on RNA viral quasispecies. Large population passages of foot-and-mouth disease …
[PDF][PDF] Docking structures of domains into maps from cryo-electron microscopy using local correlation
AM Roseman - Acta Crystallographica Section D: Biological …, 2000 - journals.iucr.org
Accurate maps of large macromolecular complexes can be calculated from cryo-electron
micrographs of non-crystalline specimens to resolutions of about 10 Å. A method to dock the …
micrographs of non-crystalline specimens to resolutions of about 10 Å. A method to dock the …
Antigen–antibody complexes
AB Ka**idza, K Kowal, M Chruszcz - Vertebrate and Invertebrate …, 2020 - Springer
Abstract In vertebrates, immunoglobulins (Igs), commonly known as antibodies, play an
integral role in the armamentarium of immune defense against various pathogens. After an …
integral role in the armamentarium of immune defense against various pathogens. After an …
A novel three-dimensional variant of the watershed transform for segmentation of electron density maps
N Volkmann - Journal of structural biology, 2002 - Elsevier
Electron density maps at moderate resolution are often difficult to interpret due to the lack of
recognizable features. This is especially true for electron tomograms that suffer in addition to …
recognizable features. This is especially true for electron tomograms that suffer in addition to …
Specificity of the VP1 GH loop of foot-and-mouth disease virus for αv integrins
Foot-and-mouth disease virus (FMDV) can use a number of integrins as receptors to initiate
infection. Attachment to the integrin is mediated by a highly conserved arginine-glycine …
infection. Attachment to the integrin is mediated by a highly conserved arginine-glycine …