The nucleolus is the most prominent nuclear body and serves a fundamentally important
biological role as a site of ribonucleoprotein particle assembly, primarily dedicated to …

Ki-67 protein has been widely used as a proliferation marker for human tumor cells for
decades. In recent studies, multiple molecular functions of this large protein have become …

Engineered skin substitutes derived from human skin significantly reduce inflammatory
reactions mediated by foreign/artificial materials and are consequently easier to use for …

Ki-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene
coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are …

Ki67 staining is widely used as a proliferation indicator in the clinic, despite poor
understanding of this protein's function or dynamics. Here, we track Ki67 levels under …

Newer treatment strategy based on proliferative nuclear marker Ki-67 targeted therapy holds
promise for prioritized/personalized treatment options with regard to improved survival and …

Eukaryotic genomes are partitioned into chromosomes that form compact and spatially well-
separated mechanical bodies during mitosis,,. This enables chromosomes to move …

Since the 2015 WHO classification was introduced into clinical practice,
immunohistochemistry (IHC) has figured prominently in lung cancer diagnosis. In addition to …

The cell proliferation antigen Ki-67 is widely used in cancer histopathology, but estimations
of Ki-67 expression levels are inconsistent and understanding of its regulation is limited …

CD4+ Foxp3+ regulatory T-cells (Tregs) are a unique subset of helper T-cells, which
regulate immune response and establish peripheral tolerance. Tregs not only maintain the …