Bone sarcomas, although rare, are associated with significant morbidity and mortality. The
most frequent primary bone cancers include osteosarcoma, chondrosarcoma and Ewing …

The Hedgehog signaling pathway is one of the fundamental pathways required for
development and regulation of postnatal regeneration in a variety of tissues. The pathway …

Una de las situaciones más claras de estos cambios son las relaciones laborales y el
cumplimiento de las obligaciones derivadas de estas, las cuales en la gran mayoría de …

Sarcomas represent one of the most challenging tumor types to treat due to their diverse
nature and our incomplete understanding of their underlying biology. Recent work suggests …

Voltage-gated sodium (Na V) channels, initially characterized in excitable cells, have been
shown to be aberrantly expressed in non-excitable cancer tissues and cells from epithelial …

Simple Summary Osteosarcoma, Ewing's sarcoma, and H3K27M-mutant diffuse midline
glioma are rare but aggressive malignancies occurring mainly in children. Due to their …

Occurrence of extraskeletal Ewing sarcoma (ES) in the gastrointestinal (GI) tract is extremely
rare. Here, we report 25 cases of ES arising primarily in the GI tract with a focus on the …

Background: Though the incidence of primary malignant bone tumors is relatively low, the
mortality related to them is disproportionately high, especially among teenagers and young …

Br east Ca ncer 1 (BRCA1) gene is a well-characterized tumor suppressor gene, mutations
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …

Ewing Sarcoma (EWS) is the second most common osseous malignancy in children and
young adults after osteosarcoma, while it is the fifth common osseous malignancy within …