▪ Abstract Human immunodeficiency virus (HIV) and other retroviruses acquire their
envelopes and spread infection by budding through the limiting membranes of producer …

Viruses have evolved complex and dynamic interactions with their host cell. In recent years
we have gained insight into the expanding roles for host lipids in the virus life cycle. In …

Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …

Antiretroviral therapies efficiently block HIV-1 replication but need to be maintained for life.
Moreover, chronic inflammation is a hallmark of HIV-1 infection that persists despite …

Tetherin, also known as BST2, CD317 or HM1. 24, was recently identified as an interferon-
inducible host–cell factor that interferes with the detachment of virus particles from infected …

Little is known about the protective role of inflammatory processes in modulating lipid
metabolism in infection. Here we report an intimate link between the innate immune …

Several steps of HIV-1 replication critically depend on cholesterol. HIV infection is
associated with profound changes in lipid and lipoprotein metabolism and an increased risk …

During the last two decades, the profusion of HIV research due to the urge to identify new
therapeutic targets has led to a wealth of information on the retroviral replication cycle …

Human immunodeficiency virus (HIV)-1 infectivity requires actin-dependent clustering of
host lipid raft–associated receptors, a process that might be linked to Rho guanosine …

Human immunodeficiency virus type 1 (HIV-1) utilizes Vpu, Env, and Nef to down-modulate
its primary CD4 receptor from the cell surface, and this function seems to be critical for the …