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Betulin and betulinic acid: Triterpenoids derivatives with a powerful biological potential
A Hordyjewska, A Ostapiuk, A Horecka… - Phytochemistry …, 2019 - Springer
Betulin, a pentacyclic triterpene and a plant pentacyclic triterpene metabolite, can be found
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …
Pharmacological activities of natural triterpenoids and their therapeutic implications
Covering: 1990–2005. Previous review: Nat. Prod. Rep., 2005, 22, 487 This article reviews
the pharmacological activity of naturally occurring triterpenoids excluding the degraded …
the pharmacological activity of naturally occurring triterpenoids excluding the degraded …
[PDF][PDF] Biological activities of lupeol
MBC Gallo, MJ Sarachine - Int. J. Biomed. Pharm. Sci, 2009 - globalsciencebooks.info
This review covers mainly the past 25 years of research on the biological activities of lupeol,
a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms …
a significant lupane-type triterpene represented in the plant, fungi and animal kingdoms …
Betulinic acid and its derivatives as potential antitumor agents
Betulinic acid (BA) is a lupane‐type pentacyclic triterpene, distributed ubiquitously
throughout the plant kingdom. BA and its derivatives demonstrate multiple bioactivities …
throughout the plant kingdom. BA and its derivatives demonstrate multiple bioactivities …
Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog
Betulinic acid (BA) and its derivatives are a class of high-profile drug candidates, but their
anticancer effects on resistant cancer have rarely been reported. Although a few studies …
anticancer effects on resistant cancer have rarely been reported. Although a few studies …
Betulinic acid: recent advances in chemical modifications, effective delivery, and molecular mechanisms of a promising anticancer therapy
An important method of drug discovery is examination of diverse life forms, including
medicinal plants and natural products or bioactive compounds isolated from these sources …
medicinal plants and natural products or bioactive compounds isolated from these sources …
Rearrangement of N-Oxyenamines and Related Reactions
AA Tabolin, SL Ioffe - Chemical Reviews, 2014 - ACS Publications
Hydroxylamines and their derivatives have found a wide range of applications in organic
synthesis. 1 In this review we hope to cover the synthetic applications of N …
synthesis. 1 In this review we hope to cover the synthetic applications of N …
Pentacyclic triterpenoids with nitrogen-and sulfur-containing heterocycles: synthesis and medicinal significance
M Kvasnica, M Urban, NJ Dickinson, J Sarek - Natural product reports, 2015 - pubs.rsc.org
Covering: 1962 to 2014 Triterpenoids are natural compounds with a variety of biological
activities and are usually produced by plants as secondary metabolites. In recent decades …
activities and are usually produced by plants as secondary metabolites. In recent decades …
Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents
RY Kuo, K Qian, SL Morris-Natschke, KH Lee - Natural product reports, 2009 - pubs.rsc.org
Covering: January 2006 to December 2008 This article reviews the antitumor and anti-HIV
activities of naturally occurring triterpenoids, including the lupane, ursane, oleanane …
activities of naturally occurring triterpenoids, including the lupane, ursane, oleanane …
Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity
RC Santos, JAR Salvador, S Marín… - Bioorganic & medicinal …, 2009 - Elsevier
A series of new imidazole carboxylic esters (carbamates) and N-acylimidazole derivatives of
betulin and betulinic acid (14–29) have been synthesized. The new compounds were …
betulin and betulinic acid (14–29) have been synthesized. The new compounds were …