Corneal neovascularization: an anti-VEGF therapy review

JH Chang, NK Garg, E Lunde, KY Han, S Jain… - Survey of …, 2012 - Elsevier
Corneal neovascularization is a serious condition that can lead to a profound decline in
vision. The abnormal vessels block light, cause corneal scarring, compromise visual acuity …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct the light path to the retina, and hence is a major cause of …

FTO regulates ocular angiogenesis via m6A-YTHDF2-dependent mechanism

K Shan, R Zhou, J **ang, Y Sun, C Liu, M Lv… - Experimental eye …, 2020 - Elsevier
Pathological ocular angiogenesis commonly results in visual impairment or even blindness.
Unveiling the mechanisms of pathological angiogenesis is critical to identify the regulators …

Corneal neovascularization and biological therapy

OB Voiculescu, LM Voinea… - Journal of medicine …, 2015 - pmc.ncbi.nlm.nih.gov
Corneal avascularity is necessary for the preservation of optimal vision. The cornea
maintains a dynamic balance between pro-and antiangiogenic factors that allows it to …

Lipid keratopathy: a review of pathophysiology, differential diagnosis, and management

MGN Hall, M Moshirfar, A Amin-Javaheri… - Ophthalmology and …, 2020 - Springer
Lipid keratopathy is a disease in which fat deposits accumulate in the cornea, leading to
opacification and decrease of visual acuity. This condition can be idiopathic without signs of …

Vascular endothelial growth factor inhibitors for treatment of corneal neovascularization: a meta-analysis

M Papathanassiou, S Theodoropoulou, A Analitis… - Cornea, 2013 - journals.lww.com
Purpose: To evaluate the therapeutic effect of bevacizumab (Avastin) on corneal
neovascularization (NV). Methods: Systematic review and meta-analysis of the literature was …

CD8+ T cells suppress viral replication in the cornea but contribute to VEGF-C–induced lymphatic vessel genesis

CD Conrady, M Zheng, DU Stone… - The Journal of …, 2012 - journals.aai.org
HSV-1 is the leading cause of infectious corneal blindness in the industrialized world. CD4+
T cells are thought to be the major leukocyte population mediating immunity to HSV-1 in the …

Understanding lymphangiogenesis in knockout models, the cornea, and ocular diseases for the development of therapeutic interventions

JF Yang, A Walia, Y Huang, K Han, MI Rosenblatt… - Survey of …, 2016 - Elsevier
A major focus of cancer research for several decades has been understand the ability of
tumors to induce new blood vessel formation, a process known as angiogenesis …

Comparison of the effects of subconjunctival and topical anti-VEGF therapy (bevacizumab) on experimental corneal neovascularization

O OzDEMIR, O Altintas, L Altintas, B OzKAN… - Arquivos brasileiros de …, 2014 - SciELO Brasil
Purpose: To compare the effects of bevacizumab applied either subconjunctivally or
topically, in a rat model of corneal neovascularization induced by alkali burn. Methods: The …

Herpeskeratitis

B Seitz, A Heiligenhaus - Der Ophthalmologe, 2011 - Springer
Zusammenfassung Herpes-simplex-Virus (HSV) ist eine sehr häufige Ursache der
Keratitis.„Die Herpeskeratitis “ist ein Chamäleon, jedoch heute gut behandelbar, wenn man …