[HTML][HTML] Applications of machine vision in pharmaceutical technology: A review

DL Galata, LA Meszaros, N Kallai-Szabo… - European Journal of …, 2021 - Elsevier
The goal of this paper is to give an introduction to analysis of images acquired by a digital
camera with visible illumination and to review its applications as a Process Analytical …

Recent advances in in-process characterization of suspensions and slurries

DM Scott - Powder Technology, 2022 - Elsevier
A comprehensive literature review was conducted on new and emerging methods for in-
process characterization of suspensions and slurries. The 152 publications reviewed here …

Characterizing variability in lignocellulosic biomass: a review

J Yan, O Oyedeji, JH Leal, BS Donohoe… - ACS Sustainable …, 2020 - ACS Publications
Feedstock variability is a significant barrier to the scale-up and commercialization of
lignocellulosic biofuel technologies. Variability in feedstock characteristics and behavior …

Fluidized bed drying of blackberry wastes: Drying kinetics, particle characterization and nutritional value of the obtained granular solids

A Sozzi, M Zambon, G Mazza, D Salvatori - Powder Technology, 2021 - Elsevier
Particulate systems for functional ingredient development were obtained by fluidized bed
drying of blackberry wastes. Fluidization behavior, drying characteristics, and …

In Situ Imaging Combined with Deep Learning for Crystallization Process Monitoring: Application to Cephalexin Production

H Salami, MA McDonald, AS Bommarius… - … Process Research & …, 2021 - ACS Publications
The online detection of a trace amount of an undesired solid phase within a crystal slurry
can enable feedback control to improve product purity, decrease batch rejection, and …

Harnessing Birefringence for Real-Time Classification of Molecular Crystals Using Dynamic Polarized Light Microscopy, Microfluidics, and Machine Learning

AYH Chua, EWQ Yeap, DM Walker… - Crystal Growth & …, 2024 - ACS Publications
Molecular crystals are ubiquitous in a variety of industrial contexts, from foods to chemicals
and pharmaceuticals. The timely identification of different molecular crystal forms (and …

Particle characterization with on-line imaging and neural network image analysis

Y Wu, M Lin, S Rohani - Chemical Engineering Research and Design, 2020 - Elsevier
We proposed a deep learning-based in situ microscopic image analysis system for detecting
particles and performing size analysis in a high-density slurry, which shows great potential …

Process analytical technology in Downstream-Processing of Drug Substances–A review

P Neugebauer, M Zettl, D Moser, J Poms… - International Journal of …, 2024 - Elsevier
Abstract Process Analytical Technology (PAT) has revolutionized pharmaceutical
manufacturing by providing real-time monitoring and control capabilities throughout the …

Sensor Fusion and Calibration-Based Adaptive Image Analysis Procedure for In Situ Crystal Size Measurement

WL Wu, MM Mills, U Schacht, C Rabinowitz… - Crystal Growth & …, 2023 - ACS Publications
Traditionally, off-line measurements via image analysis or laser diffraction methods are used
to analyze the crystal product. It is often beneficial to extract crystal samples intermittently …

[HTML][HTML] Engineering of acetaminophen particle attributes using a wet milling crystallisation platform

B Ahmed, CJ Brown, T McGlone, DL Bowering… - International Journal of …, 2019 - Elsevier
Wet milling coupled with crystallisation has considerable potential to deliver enhanced
control over particle attributes. The effect of process conditions and wet mill configuration on …