Juvenile myoclonic epilepsy: a system disorder of the brain

P Wolf, EMT Yacubian, G Avanzini, T Sander… - Epilepsy research, 2015 - Elsevier
The prevailing understanding of generalized epilepsy is shaped by the traditional definition
that “the responsible neuronal discharge takes place, if not throughout the entire grey matter …

Understanding ictogenesis in generalized epilepsies

P Wolf, S Beniczky - Expert review of neurotherapeutics, 2014 - Taylor & Francis
Generalized seizures are defined by bilateral symmetric and synchronous epileptiform EEG
discharge over the entire convexity and commonly thought to involve the entire brain …

[HTML][HTML] Dynamic flexibility and controllability of network communities in juvenile myoclonic epilepsy

A Vataman, D Ciolac, V Chiosa, D Aftene… - Neurobiology of …, 2023 - Elsevier
Juvenile myoclonic epilepsy (JME) is the most common syndrome within the idiopathic
generalized epilepsy spectrum, manifested by myoclonic and generalized tonic-clonic …

[HTML][HTML] Hyperconnectivity in juvenile myoclonic epilepsy: a network analysis

K Caeyenberghs, HWR Powell, RH Thomas… - NeuroImage: Clinical, 2015 - Elsevier
Objective Juvenile myoclonic epilepsy (JME) is a common idiopathic (genetic) generalized
epilepsy (IGE) syndrome characterized by impairments in executive and cognitive control …

Causality analysis to the abnormal subcortical–cortical connections in idiopathic-generalized epilepsy

Y Qin, S Li, D Yao, C Luo - Frontiers in Neuroscience, 2022 - frontiersin.org
Idiopathic generalized epilepsy (IGE) was characterized by 3–6 Hz generalized spike-wave
discharges (GSWDs), and extensive altered interactions in subcortical-cortical circuit …

[HTML][HTML] Juvenile myoclonic epilepsy shows increased posterior theta, and reduced sensorimotor beta resting connectivity

B Routley, A Shaw, SD Muthukumaraswamy… - Epilepsy Research, 2020 - Elsevier
Background Widespread structural and functional brain network changes have been shown
in Juvenile Myoclonic Epilepsy (JME) despite normal clinical neuroimaging. We sought to …

Information transmission in mPFC-BLA network during exploratory behavior in the open field

X Bao, C Qi, T Liu, X Zheng - Behavioural Brain Research, 2021 - Elsevier
Exploratory behavior plays a fundamental role in motivation, learning, and well-being of
organisms. The open field test (OFT) is a classic method to investigate the exploratory …

[HTML][HTML] Altered dynamic effective connectivity of the default mode network in newly diagnosed drug-naïve juvenile myoclonic epilepsy

Z Zhang, G Liu, W Zheng, J Shi, H Liu, Y Sun - NeuroImage: Clinical, 2020 - Elsevier
Juvenile myoclonic epilepsy (JME) has been repeatedly revealed to be associated with
brain dysconnectivity in the default mode network (DMN). However, the implicit assumption …

How alpha rhythm spatiotemporally acts upon the thalamus-default mode circuit in idiopathic generalized epilepsy

Y Qin, N Zhang, Y Chen, Y Tan, L Dong… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Goal: Idiopathic generalized epilepsy (IGE) represents generalized spike-wave discharges
(GSWD) and distributed changes in thalamocortical circuit. The purpose of this study is to …

Energy landscape of resting magnetoencephalography reveals fronto-parietal network impairments in epilepsy

D Krzemiński, N Masuda, K Hamandi, KD Singh… - Network …, 2020 - direct.mit.edu
Juvenile myoclonic epilepsy (JME) is a form of idiopathic generalized epilepsy. It is yet
unclear to what extent JME leads to abnormal network activation patterns. Here, we …