Novel and emerging treatments for major depression
Depression is common, costly, debilitating, and associated with increased risk of suicide. It is
one of the leading global public health problems. Although existing available …
one of the leading global public health problems. Although existing available …
Major depressive disorder: hypothesis, mechanism, prevention and treatment
L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - Signal transduction and …, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials
Non-invasive brain stimulation (NIBS), including transcranial magnetic stimulation (TMS),
and transcranial direct current stimulation (tDCS), is a potentially effective treatment strategy …
and transcranial direct current stimulation (tDCS), is a potentially effective treatment strategy …
Electroconvulsive therapy
RT Espinoza, CH Kellner - New England Journal of Medicine, 2022 - Mass Medical Soc
Update on Electroconvulsive Therapy ECT is effective for several disorders, particularly
severe or treatment-resistant depression, with a rapid response, but stigma has impeded its …
severe or treatment-resistant depression, with a rapid response, but stigma has impeded its …
The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …
derived from scientific evidence and supplemented by expert clinical consensus to formulate …
Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation in neurological and psychiatric disorders
F Fregni, MM El-Hagrassy… - International Journal …, 2021 - academic.oup.com
Background Transcranial direct current stimulation has shown promising clinical results,
leading to increased demand for an evidence-based review on its clinical effects. Objective …
leading to increased demand for an evidence-based review on its clinical effects. Objective …
Comorbid depression in medical diseases
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …
Diagnosis and management of bipolar disorders
FS Goes - bmj, 2023 - bmj.com
Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …
around 2% of the world's population and encompass a spectrum between severe elevated …
Management of treatment-resistant depression: challenges and strategies
Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …
which does not respond to traditional and first-line therapeutic options. There are several …
Management of depression in adults: a review
Importance Approximately 9% of US adults experience major depression each year, with a
lifetime prevalence of approximately 17% for men and 30% for women. Observations Major …
lifetime prevalence of approximately 17% for men and 30% for women. Observations Major …