Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies
BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …
research based on biologically accurate screening approaches. Since establishing the 2D in …
Perspectives for self-driving labs in synthetic biology
Highlights•Self-driving labs (SDLs) combine automated experiments with AI to direct
them.•Synthetic biology provides a unique opportunity for the development of SDLs.•The …
them.•Synthetic biology provides a unique opportunity for the development of SDLs.•The …
Biological research and self-driving labs in deep space supported by artificial intelligence
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …
organisms, develop foundational knowledge to support deep space exploration and …
Enabling pathway design by multiplex experimentation and machine learning
AG Boob, J Chen, H Zhao - Metabolic Engineering, 2024 - Elsevier
The remarkable metabolic diversity observed in nature has provided a foundation for
sustainable production of a wide array of valuable molecules. However, transferring the …
sustainable production of a wide array of valuable molecules. However, transferring the …
Microfluidics: a concise review of the history, principles, design, applications, and future outlook
MI Hajam, MM Khan - Biomaterials Science, 2024 - pubs.rsc.org
Microfluidic technologies have garnered significant attention due to their ability to rapidly
process samples and precisely manipulate fluids in assays, making them an attractive …
process samples and precisely manipulate fluids in assays, making them an attractive …
An outlook on the current challenges and opportunities in DNA data storage
Silicon is the gold standard for information storage systems. The exponential generation of
digital information will exhaust the global supply of refined silicon. Therefore, investing in …
digital information will exhaust the global supply of refined silicon. Therefore, investing in …
Automated in vivo enzyme engineering accelerates biocatalyst optimization
Achieving cost-competitive bio-based processes requires development of stable and
selective biocatalysts. Their realization through in vitro enzyme characterization and …
selective biocatalysts. Their realization through in vitro enzyme characterization and …
Periodic flows in microfluidics
Microfluidics, the science and technology of manipulating fluids in microscale channels,
offers numerous advantages, such as low energy consumption, compact device size …
offers numerous advantages, such as low energy consumption, compact device size …
Artificial intelligence-enabled multipurpose smart detection in active-matrix electrowetting-on-dielectric digital microfluidics
An active-matrix electrowetting-on-dielectric (AM-EWOD) system integrates hundreds of
thousands of active electrodes for sample droplet manipulation, which can enable …
thousands of active electrodes for sample droplet manipulation, which can enable …
Recent advances in the use of the CRISPR-Cas system for the detection of infectious pathogens
H Gao, Z Shang, SY Chan, D Ma - Journal of Zhejiang University …, 2022 - Springer
Infectious diseases cause great economic loss and individual and even social anguish.
Existing detection methods lack sensitivity and specificity, have a poor turnaround time, and …
Existing detection methods lack sensitivity and specificity, have a poor turnaround time, and …