Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

During evolution, individuals whose brains and bodies functioned well in a fasted state were
successful in acquiring food, enabling their survival and reproduction. With fasting and …

A significant body of work has investigated the effects of acute exercise, defined as a single
bout of physical activity, on mood and cognitive functions in humans. Several excellent …

Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

No medications prevent or reverse age-related cognitive decline. Physical activity (PA)
enhances memory in rodents, but findings are mixed in human studies. As a result, exercise …

Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Earlier observations in neuroscience suggested that no new neurons form in the mature
central nervous system. Evidence now indicates that new neurons do form in the adult …

Physical exercise can convey a protective effect against cognitive decline in ageing and
Alzheimer's disease. While the long-term health-promoting and protective effects of exercise …

In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …

Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …