Pathogenic Escherichia coli

JB Kaper, JP Nataro, HLT Mobley - Nature reviews microbiology, 2004 - nature.com
Few microorganisms are as versatile as Escherichia coli. An important member of the
normal intestinal microflora of humans and other mammals, E. coli has also been widely …

Recent advances in understanding enteric pathogenic Escherichia coli

MA Croxen, RJ Law, R Scholz… - Clinical microbiology …, 2013 - Am Soc Microbiol
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Molecular mechanisms of Escherichia coli pathogenicity

MA Croxen, BB Finlay - Nature Reviews Microbiology, 2010 - nature.com
Escherichia coli is a remarkable and diverse organism. This normally harmless commensal
needs only to acquire a combination of mobile genetic elements to become a highly adapted …

The WASP–WAVE protein network: connecting the membrane to the cytoskeleton

T Takenawa, S Suetsugu - Nature reviews Molecular cell biology, 2007 - nature.com
Wiskott–Aldrich syndrome protein (WASP) and WASP-family verprolin-homologous protein
(WAVE) family proteins are scaffolds that link upstream signals to the activation of the …

Cellular control of actin nucleation

MD Welch, RD Mullins - Annual review of cell and …, 2002 - annualreviews.org
▪ Abstract Eukaryotic cells use actin polymerization to change shape, move, and internalize
extracellular materials by phagocytosis and endocytosis, and to form contractile structures …

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation

M Stein, R Rappuoli, A Covacci - Proceedings of the …, 2000 - National Acad Sciences
Helicobacter pylori strains associated with severe tissue damage and inflammation possess
a unique genetic locus, cag, containing 31 genes originating from a distant event of …

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

S Srinivasan, F Wang, S Glavas, A Ott… - The Journal of cell …, 2003 - rupress.org
Neutrophils exposed to chemoattractants polarize and accumulate polymerized actin at the
leading edge. In neutrophil-like HL-60 cells, this asymmetry depends on a positive feedback …

c‐Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs

M Stein, F Bagnoli, R Halenbeck… - Molecular …, 2002 - Wiley Online Library
The human pathogen Helicobacter pylori colonizes the mucous layer of the stomach. During
parasitic infection, freely swimming bacteria adhere to the gastric epithelial cells and trigger …

Enteropathogenic and Enterohemorrhagic Escherichia coli Infections: Translocation, Translocation, Translocation

J Garmendia, G Frankel, VF Crepin - Infection and immunity, 2005 - Am Soc Microbiol
Escherichia coli is the most abundant facultative anaerobic gram-negative bacterium of the
intestinal microffora, naturally colonizing the mucous layer of the colon. A conserved core …

Enteropathogenic Escherichia coli: unravelling pathogenesis

H Deborah Chen, G Frankel - FEMS microbiology reviews, 2005 - academic.oup.com
Enteropathogenic Escherichia coli (EPEC) is a gram-negative bacterial pathogen that
adheres to intestinal epithelial cells, causing diarrhoea. It constitutes a significant risk to …