Population genomics of rapid adaptation by soft selective sweeps

PW Messer, DA Petrov - Trends in ecology & evolution, 2013 - cell.com
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …

Neonicotinoid insecticide toxicology: mechanisms of selective action

M Tomizawa, JE Casida - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract The neonicotinoids, the newest major class of insecticides, have outstanding
potency and systemic action for crop protection against piercing-sucking pests, and they are …

Recent Selective Sweeps in North American Drosophila melanogaster Show Signatures of Soft Sweeps

NR Garud, PW Messer, EO Buzbas, DA Petrov - PLoS genetics, 2015 - journals.plos.org
Adaptation from standing genetic variation or recurrent de novo mutation in large
populations should commonly generate soft rather than hard selective sweeps. In contrast to …

Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptors

M Tomizawa, JE Casida - Annual review of entomology, 2003 - annualreviews.org
▪ Abstract Neonicotinoids, the most important new class of synthetic insecticides of the past
three decades, are used to control sucking insects both on plants and on companion …

Neonicotinoids—from zero to hero in insecticide chemistry

P Jeschke, R Nauen - Pest Management Science: formerly …, 2008 - Wiley Online Library
In recent years, neonicotinoids have been the fastest‐growing class of insecticides in
modern crop protection, with widespread use against a broad spectrum of sucking and …

A Single P450 Allele Associated with Insecticide Resistance in Drosophila

PJ Daborn, JL Yen, MR Bogwitz, G Le Goff, E Feil… - Science, 2002 - science.org
Insecticide resistance is one of the most widespread genetic changes caused by human
activity, but we still understand little about the origins and spread of resistant alleles in global …

Guidelines on nicotine dose selection for in vivo research

SG Matta, DJ Balfour, NL Benowitz, RT Boyd… - …, 2007 - Springer
Rationale This review provides insight for the judicious selection of nicotine dose ranges
and routes of administration for in vivo studies. The literature is replete with reports in which …

CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae

CV Edi, L Djogbenou, AM Jenkins, K Regna… - PLoS …, 2014 - journals.plos.org
Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in
Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative …

Resistance of insect pests to neonicotinoid insecticides: current status and future prospects

R Nauen, I Denholm - Archives of insect biochemistry and …, 2005 - Wiley Online Library
The first neonicotinoid insecticide introduced to the market was imidacloprid in 1991
followed by several others belonging to the same chemical class and with the same mode of …

Neonicotinoid metabolism: compounds, substituents, pathways, enzymes, organisms, and relevance

JE Casida - Journal of agricultural and food chemistry, 2011 - ACS Publications
Neonicotinoids are one of the three principal insecticide chemotypes. The seven major
commercial neonicotinoids are readily biodegraded by metabolic attack at their N …