Imagination as a fundamental function of the hippocampus

AE Comrie, LM Frank, K Kay - … Transactions of the …, 2022‏ - royalsocietypublishing.org
Imagination is a biological function that is vital to human experience and advanced
cognition. Despite this importance, it remains unknown how imagination is realized in the …

Learning, fast and slow: Single-and many-shot learning in the hippocampus

Z Liao, A Losonczy - Annual Review of Neuroscience, 2024‏ - annualreviews.org
The hippocampus is critical for memory and spatial navigation. The ability to map novel
environments, as well as more abstract conceptual relationships, is fundamental to the …

Contributions of cortical neuron firing patterns, synaptic connectivity, and plasticity to task performance

MN Insanally, BF Albanna, J Toth… - Nature …, 2024‏ - nature.com
Neuronal responses during behavior are diverse, ranging from highly reliable
'classical'responses to irregular 'non-classically responsive'firing. While a continuum of …

Human voltage-gated Na+ and K+ channel properties underlie sustained fast AP signaling

R Wilbers, VD Metodieva, S Duverdin, DB Heyer… - Science …, 2023‏ - science.org
Human cortical pyramidal neurons are large, have extensive dendritic trees, and yet have
unexpectedly fast input-output properties: Rapid subthreshold synaptic membrane potential …

Induced neural phase precession through exogenous electric fields

M Wischnewski, H Tran, Z Zhao, S Shirinpour… - Nature …, 2024‏ - nature.com
The gradual shifting of preferred neural spiking relative to local field potentials (LFPs),
known as phase precession, plays a prominent role in neural coding. Correlations between …

Phase separation of competing memories along the human hippocampal theta rhythm

C Kerrén, S van Bree, BJ Griffiths, M Wimber - Elife, 2022‏ - elifesciences.org
Competition between overlap** memories is considered one of the major causes of
forgetting, and it is still unknown how the human brain resolves such mnemonic conflict. In …

Patterns of synchronized clusters in adaptive networks

M Lodi, S Panahi, F Sorrentino, A Torcini… - Communications …, 2024‏ - nature.com
Adaptive networks with time-varying connectivity, often called plasticity, provide a
fundamental paradigm to model complex dynamical systems. In these systems, different …

Morpho-electric diversity of human hippocampal CA1 pyramidal neurons

EJ Mertens, Y Leibner, J Pie, AA Galakhova… - Cell reports, 2024‏ - cell.com
Hippocampal pyramidal neuron activity underlies episodic memory and spatial navigation.
Although extensively studied in rodents, extremely little is known about human hippocampal …

[HTML][HTML] Fronto-medial theta coordinates posterior maintenance of working memory content

O Ratcliffe, K Shapiro, BP Staresina - Current Biology, 2022‏ - cell.com
How does the human brain manage multiple bits of information to guide goal-directed
behavior? Successful working memory (WM) functioning has consistently been linked to …

Theta oscillations support prefrontal-hippocampal interactions in sequential working memory

M Su, K Hu, W Liu, Y Wu, T Wang, C Cao, B Sun… - Neuroscience …, 2024‏ - Springer
The prefrontal cortex and hippocampus may support sequential working memory beyond
episodic memory and spatial navigation. This stereoelectroencephalography (SEEG) study …