Animal domestication is considered a complex and multistage process that altered
behaviorally, morphologically, and physiologically the domesticates relative to their wild …

The horse was domesticated only 5.5 KYA, thousands of years after dogs, cattle, pigs,
sheep, and goats. The horse nonetheless represents the domestic animal that most …

The genomic changes underlying both early and late stages of horse domestication remain
largely unknown. We examined the genomes of 14 early domestic horses from the Bronze …

The domestication of the horse∼ 5.5 kya and the emergence of mounted riding, chariotry,
and cavalry dramatically transformed human civilization. However, the genetics underlying …

Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …

The Arabian horse, one of the world's oldest breeds of any domesticated animal, is
characterized by natural beauty, graceful movement, athletic endurance, and, as a result of …

Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …

Disease-causing variants have been identified for less than 20% of suspected equine
genetic diseases. Whole genome sequencing (WGS) allows rapid identification of rare …

The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Small effective population sizes and active inbreeding can lead to inbreeding depression
due to deleterious recessive mutations exposed in the homozygous state. The …