Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …

Arrest of ongoing movements is an integral part of executing motor programs. Behavioral
arrest may happen upon termination of a variety of goal-directed movements or as a global …

Recent evidence from monkey models of cognition shows that the magnocellular
subdivision of the mediodorsal thalamus (MDmc) is more critical for learning new …

Adolescence is a time during which we transition to independence, explore new activities
and begin pursuit of major life goals. Goal-directed learning, in which we learn to perform …

The thalamic parafascicular nucleus (PF), an excitatory input to the basal ganglia, is targeted
with deep-brain stimulation to alleviate a range of neuropsychiatric symptoms. Furthermore …

Because of our limited knowledge of the functional role of the thalamostriatal system, this
massive network is often ignored in models of the pathophysiology of brain disorders of …

Making decisions in environments with few choice options is easy. We select the action that
results in the most valued outcome. Making decisions in more complex environments, where …

The main impetus for a mini-symposium on corticothalamic interrelationships was the recent
number of studies highlighting the role of the thalamus in aspects of cognition beyond …

Dystonia is a movement disorder of both genetic and non-genetic causes, which typically
results in twisted posturing due to abnormal muscle contraction. Evidence from dystonia …