Tortuous arteries and veins are commonly observed in humans and animals. While mild
tortuosity is asymptomatic, severe tortuosity can lead to ischemic attack in distal organs …

Chronic cerebral hypoperfusion has been associated with cognitive decline in aging and
Alzheimer's disease. Moreover, the pattern of cerebral blood flow in mild cognitive …

Vascular cognitive impairment (VCI) or vascular dementia occurs as a result of brain
ischemia and represents the second most common type of dementia after Alzheimer's …

Ischemic tolerance describes the adaptive biological response of cells and organs that is
initiated by preconditioning (ie, exposure to stressor of mild severity) and the associated …

Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery
blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field …

Reduction of cerebral blood flow is an important risk factor for dementia states and other
brain dysfunctions. In present study, the effects of permanent occlusion of common carotid …

Chronic cerebral hypoperfusion (CCH) induces cognitive impairment, but the compensative
mechanism of cerebral blood flow (CBF) is not fully understood. The present study mainly …

Despite the large body of data available, chronic cerebral hypoperfusion lacks an operative
definition. In a tautological way, the term hypoperfusion is being referred to conditions of …

Aims White matter damage is the main pathological feature of chronic cerebral
hypoperfusion (CCH) and glial activation is crucial in this process. Physical exercise has …

Myelin is closely associated with cognitive function and is extremely vulnerable to damage
in ischemic cerebrovascular diseases. The failure of remyelination is mainly due to …