Biodiscoveryagent: An ai agent for designing genetic perturbation experiments

Y Roohani, A Lee, Q Huang, J Vora, Z Steinhart… - arxiv preprint arxiv …, 2024 - arxiv.org
Agents based on large language models have shown great potential in accelerating
scientific discovery by leveraging their rich background knowledge and reasoning …

[HTML][HTML] Large Language Models, scientific knowledge and factuality: A framework to streamline human expert evaluation

M Wysocka, O Wysocki, M Delmas, V Mutel… - Journal of Biomedical …, 2024 - Elsevier
Objective: The paper introduces a framework for the evaluation of the encoding of factual
scientific knowledge, designed to streamline the manual evaluation process typically …

Pathway-based analyses of gene expression profiles at low doses of ionizing radiation

X Luo, S Niyakan, P Johnstone, S McCorkle… - Frontiers in …, 2024 - frontiersin.org
Radiation exposure poses a significant threat to human health. Emerging research indicates
that even low-dose radiation once believed to be safe, may have harmful effects. This …

[HTML][HTML] A Comprehensive Evaluation of Large Language Models in Mining Gene Interactions and Pathway Knowledge

M Azam, Y Chen, MO Arowolo, H Liu, M Popescu, D Xu - bioRxiv, 2024 - ncbi.nlm.nih.gov
Background: Understanding complex biological pathways, including gene-gene interactions
and gene regulatory networks, is critical for exploring disease mechanisms and drug …

Density estimation via measure transport: Outlook for applications in the biological sciences

V López‐Marrero, PR Johnstone… - Statistical Analysis and …, 2024 - Wiley Online Library
One among several advantages of measure transport methods is that they allow or a unified
framework for processing and analysis of data distributed according to a wide class of …

GeneRAG: Enhancing Large Language Models with Gene-Related Task by Retrieval-Augmented Generation

X Lin, G Deng, Y Li, J Ge, JWK Ho, Y Liu - bioRxiv, 2024 - biorxiv.org
Abstract Large Language Models (LLMs) like GPT-4 have revolutionized natural language
processing and are used in gene analysis, but their gene knowledge is incomplete. Fine …

Large Language Models for Pathway Curation: A Preliminary Investigation

N Karkera, N Karkera, M Kumar, S Ghosh… - bioRxiv, 2024 - biorxiv.org
The pathway curation task involves analyzing scientific literature to identify and represent
cellular processes as pathways. This process, often time-consuming and labor-intensive …