Salt sensitivity of blood pressure: a scientific statement from the American Heart Association
F Elijovich, MH Weinberger, CAM Anderson… - …, 2016 - Am Heart Assoc
Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …
Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans
Compelling evidence for the inherited nature of essential hypertension has led to extensive
research in rats and humans. Rats have served as the primary model for research on the …
research in rats and humans. Rats have served as the primary model for research on the …
Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease
Long noncoding RNAs (lncRNAs) are an emerging class of genomic regulatory molecules
reported in various species. In the rat, which is one of the major mammalian model …
reported in various species. In the rat, which is one of the major mammalian model …
Circular RNAs in rat models of cardiovascular and renal diseases
Circular RNAs (circRNAs) have emerged as an important new class of genomic regulatory
molecules contributing to the development of various diseases, but their relevance to the …
molecules contributing to the development of various diseases, but their relevance to the …
Dr Lewis Kitchener Dahl, the Dahl rats, and the “inconvenient truth” about the genetics of hypertension
B Joe - Hypertension, 2015 - Am Heart Assoc
After graduating from high school, Dr Lewis Dahl moved to Seattle, Washington, to complete
his undergraduate studies at the University of Washington in 1935 (Figure 2). He then …
his undergraduate studies at the University of Washington in 1935 (Figure 2). He then …
Limited WKY chromosomal regions confer increases in anxiety and fear memory in a F344 congenic rat strain
MT Ji, N Pashankar, AM Harter… - Physiological …, 2024 - journals.physiology.org
This study investigated the interaction between genetic differences in stress reactivity/co**
and environmental challenges, such as acute stress during adolescence on adult contextual …
and environmental challenges, such as acute stress during adolescence on adult contextual …
Refined map** of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models
Previously linkage and substitution map** were conducted between the Dahl Salt-
sensitive (S) rat and the Spontaneously Hypertensive Rat (SHR) to address the hypothesis …
sensitive (S) rat and the Spontaneously Hypertensive Rat (SHR) to address the hypothesis …
Isolation and high-throughput sequencing of two closely linked epistatic hypertension susceptibility loci with a panel of bicongenic strains
Interactions or epistasis between genetic factors may contribute to “missing heritability.”
While linkage analyses detect epistasis, defining the limits of the interacting segments poses …
While linkage analyses detect epistasis, defining the limits of the interacting segments poses …
Use of contiguous congenic strains in analyzing compound QTLs
JP Rapp, B Joe - Physiological Genomics, 2012 - journals.physiology.org
Genetic analysis of polygenic traits in rats and mice has been very useful for finding the
approximate chromosomal locations of the genes causing quantitative phenotypic variation …
approximate chromosomal locations of the genes causing quantitative phenotypic variation …
Six Decades of History of Hypertension Research at the University of Toledo: Highlighting Pioneering Contributions in Biochemistry, Genetics, and Host-Microbiota …
Abstract Purpose of Review The study aims to capture the history and lineage of
hypertension researchers from the University of Toledo in Ohio and showcase their …
hypertension researchers from the University of Toledo in Ohio and showcase their …