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GFAP as a potential biomarker for Alzheimer's disease: a systematic review and meta-analysis
KY Kim, KY Shin, KA Chang - Cells, 2023 - mdpi.com
Blood biomarkers have been considered tools for the diagnosis, prognosis, and monitoring
of Alzheimer's disease (AD). Although amyloid-β peptide (Aβ) and tau are primarily blood …
of Alzheimer's disease (AD). Although amyloid-β peptide (Aβ) and tau are primarily blood …
The biological pathways of Alzheimer disease: A review
M Calabrò, C Rinaldi, G Santoro… - AIMS …, 2020 - pmc.ncbi.nlm.nih.gov
Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …
people, which severely impairs patients' quality of life. In the recent years, the number of …
Role of tau protein in Alzheimer's disease: The prime pathological player
Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
Three decades of Cdk5
Cdk5 is a proline-directed serine/threonine protein kinase that governs a variety of cellular
processes in neurons, the dysregulation of which compromises normal brain function. The …
processes in neurons, the dysregulation of which compromises normal brain function. The …
The many faces of tau
While the microtubule-binding capacity of the protein tau has been known for many years,
new functions of tau in signaling and cytoskeletal organization have recently emerged. In …
new functions of tau in signaling and cytoskeletal organization have recently emerged. In …
Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives
Z Li, B Yin, S Zhang, Z Lan, L Zhang - European Journal of Medicinal …, 2023 - Elsevier
Alzheimer's disease (AD) is a serious neurodegenerative disease characterized by memory
impairment, mental retardation, impaired motor balance, loss of self-care and even death …
impairment, mental retardation, impaired motor balance, loss of self-care and even death …
Tau is essential to β-amyloid-induced neurotoxicity
Senile plaques and neurofibrillary tangles, the two hallmark lesions of Alzheimer's disease,
are the results of the pathological deposition of proteins normally present throughout the …
are the results of the pathological deposition of proteins normally present throughout the …
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
Inflammation is a critical component of the pathogenesis of Alzheimer's disease (AD).
Although not an initiator of this disorder, inflammation nonetheless plays a pivotal role as a …
Although not an initiator of this disorder, inflammation nonetheless plays a pivotal role as a …