Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal
cord is limited by low specificity regarding the underlying pathological processes, and new …

The study of neuroanatomy using imaging enables key insights into how our brains function,
are shaped by genes and environment, and change with development, aging and disease …

Several MRI measures have been proposed as in vivo biomarkers of myelin, each with
applications ranging from plasticity to pathology. Despite the availability of these myelin …

Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

There is a broad consensus that multiple sclerosis (MS) represents more than an
inflammatory disease: it harbors several characteristic aspects of a classical …

Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic
cellular parameters holds the promise of quantifying the integrity of white matter …