[HTML][HTML] Epstein-Barr virus and systemic autoimmune diseases

G Houen, NH Trier - Frontiers in immunology, 2021 - frontiersin.org
Epstein-Barr Virus (EBV) is an extremely successful human herpes virus, which infects
essentially all human beings at some time during their life span. EBV infection and the …

CSF-1 receptor signaling in myeloid cells

ER Stanley, V Chitu - Cold Spring Harbor perspectives …, 2014 - cshperspectives.cshlp.org
The CSF-1 receptor (CSF-1R) is activated by the homodimeric growth factors colony-
stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in …

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

BH Durham, E Lopez Rodrigo, J Picarsic… - Nature medicine, 2019 - nature.com
Histiocytoses are clonal hematopoietic disorders frequently driven by mutations map** to
the BRAF and MEK1 and MEK2 kinases. Currently, however, the developmental origins of …

Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS)

MA Graewert, DI Svergun - Current opinion in structural biology, 2013 - Elsevier
Highlights•Popularity of SAXS/WAXS for structural analysis has gained substantially.•
Remarkable developments in hardware and software allow for high-throughput …

Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2

S Yang, Y Wang, F Yu, R Cheng, Y Zhang… - Nature …, 2023 - nature.com
The rapid spread of monkeypox in multiple countries has resulted in a global public health
threat and has caused international concerns since May 2022. Poxvirus encoded M2 protein …

Epstein-Barr virus-associated gastric cancer and potential mechanisms of oncogenesis

A Morales-Sanchez… - Current cancer drug …, 2017 - benthamdirect.com
Introduction: EBV-associated Gastric Cancer (EBVaGC) comprises about 9% of all cases of
GC and constitutes a distinct clinicopathological and molecular entity. The pattern of viral …

Extracellular assembly and activation principles of oncogenic class III receptor tyrosine kinases

K Verstraete, SN Savvides - Nature Reviews Cancer, 2012 - nature.com
Intracellular signalling cascades initiated by class III receptor tyrosine kinases (RTK-IIIs) and
their cytokine ligands contribute to haematopoiesis and mesenchymal tissue development …

IL-33trap is a novel IL-33–neutralizing biologic that inhibits allergic airway inflammation

A Holgado, H Braun, E Van Nuffel, S Detry… - Journal of Allergy and …, 2019 - Elsevier
Background The emergence of IL-33 as a key molecular player in the development and
propagation of widespread inflammatory diseases, including asthma and atopic dermatitis …

Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity

S Detry, J Andries, Y Bloch, C Gabay… - Journal of Biological …, 2022 - ASBMB
Human Interleukin-18 (IL-18) is an omnipresent proinflammatory cytokine of the IL-1 family
with central roles in autoimmune and inflammatory diseases and serves as a staple …

The immunomodulatory capacity of an epstein-barr virus abortive lytic cycle: potential contribution to viral tumorigenesis

A Morales-Sánchez, EM Fuentes-Panana - Cancers, 2018 - mdpi.com
Epstein-Barr virus (EBV) is characterized by a bipartite life cycle in which latent and lytic
stages are alternated. Latency is compatible with long-lasting persistency within the infected …