Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours

MT Makale, CR McDonald… - Nature Reviews …, 2017 - nature.com
Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …

Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus

M Lambrecht, DBP Eekers, C Alapetite… - Radiotherapy and …, 2018 - Elsevier
Purpose For unbiased comparison of different radiation modalities and techniques,
consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose …

Regional susceptibility to dose-dependent white matter damage after brain radiotherapy

M Connor, R Karunamuni, C McDonald… - Radiotherapy and …, 2017 - Elsevier
Background and purpose Regional differences in sensitivity to white matter damage after
brain radiotherapy (RT) are not well-described. We characterized the spatial heterogeneity …

Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults

C Wilke, D Grosshans, J Duman, P Brown… - Neuro-oncology, 2018 - academic.oup.com
Radiotherapy is ubiquitous in the treatment of patients with both primary brain tumors as well
as disease which is metastatic to the brain. This therapy is not without cost, however, as …

[HTML][HTML] Cognitive deficits in adult patients with high-grade glioma: a systematic review

K Acevedo-Vergara, M Perez-Florez, A Ramirez… - Clinical neurology and …, 2022 - Elsevier
Introduction High-grade gliomas cause cognitive impairment in those who suffer from them.
However, there is a lack of precise data describing the cognitive deficit that occurs in this …

Regional responses in radiation-induced normal tissue damage

DC Voshart, J Wiedemann, P van Luijk, L Barazzuol - Cancers, 2021 - mdpi.com
Simple Summary Side effects caused by the concomitant irradiation of normal tissue during
radiotherapy for cancer treatment can negatively affect the patient's quality of life and limit …

Neurotoxicity from old and new radiation treatments for brain tumors

R Soffietti, A Pellerino, F Bruno, A Mauro… - International Journal of …, 2023 - mdpi.com
Research regarding the mechanisms of brain damage following radiation treatments for
brain tumors has increased over the years, thus providing a deeper insight into the …

Cognitive impairment and morphological changes after radiation therapy in brain tumors: a review

J Jacob, T Durand, L Feuvret, JJ Mazeron… - Radiotherapy and …, 2018 - Elsevier
Life expectancy of patients treated for brain tumors has lengthened due to the therapeutic
improvements. Cognitive impairment has been described following brain radiotherapy, but …

Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion

J Petr, I Platzek, F Hofheinz, HJMM Mutsaerts… - Radiotherapy and …, 2018 - Elsevier
Background and purpose To compare the structural and hemodynamic changes of healthy
brain tissue in the cerebral hemisphere contralateral to the tumor following photon and …

[HTML][HTML] Proton therapy for selected low grade glioma patients in the Netherlands

HL van der Weide, MCA Kramer, D Scandurra… - Radiotherapy and …, 2021 - Elsevier
Proton therapy offers an attractive alternative to conventional photon-based radiotherapy in
low grade glioma patients, delivering radiotherapy with equivalent efficacy to the tumour with …