Brucellosis is one of the most prevalent bacterial zoonosis of worldwide distribution. The
disease is caused by Brucella spp., facultative intracellular pathogens. Brucellosis in …

Given the current pandemic the world is struggling with, there is an urgent need to
continually improve vaccine technologies. Ionizing radiation technology has a long history in …

One of the earliest methods used in the manufacture of stable and safe vaccines is the use
of chemical and physical treatments to produce inactivated forms of pathogens. Although …

Background/Objectives In spite of all the research effort for develo** new vaccines against
brucellosis, it remains unclear whether these new vaccine technologies will in fact become …

Actinomycete genomes are encoded with immense potential to produce secondary
metabolites, however standard laboratory culture experiments rarely provide the conditions …

Brucella spp. are Gram-negative, facultative intracellular coccobacilli that cause one of the
most frequently encountered zoonosis worldwide. Humans naturally acquire infection …

Background Brucellosis is a chronic bacterial disease caused by members of the genus
Brucella. Among the classical species stands Brucella neotomae, until now, a pathogen …

Brucella is a genus of gram-negative bacteria that cause brucellosis. B. abortus and B.
melitensis infect domestic ruminants while B. suis (biovars 1–3) infect swine, and all these …

Pseudomonas aeruginosa is a gram-negative bacterium and one of the leading causes of
nosocomial infection worldwide, however, no effective vaccine is currently available in the …

In 1967, Brucella neotomae was first isolated from Neotoma lepida, the dessert wood rat, in
Utah. With little infection data since its discovery, the zoonotic potential of this Brucella …