In the brain, most synapses are formed on minute protrusions known as dendritic spines.
Unlike their artificial intelligence counterparts, spines are not merely tuneable memory …

Connections between neurons can be mapped by acquiring and analysing electron
microscopic brain images. In recent years, this approach has been applied to chunks of …

The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

Due to advances in automated image acquisition and analysis, whole-brain connectomes
with 100,000 or more neurons are on the horizon. Proofreading of whole-brain automated …

Neurons in the develo** brain undergo extensive structural refinement as nascent circuits
adopt their mature form. This physical transformation of neurons is facilitated by the …

Inhibitory neurons in mammalian cortex exhibit diverse physiological, morphological,
molecular, and connectivity signatures. While considerable work has measured the average …

Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity powerfully shapes …

The posterior parietal cortex exhibits choice-selective activity during perceptual decision-
making tasks,,,,,,,,–. However, it is not known how this selective activity arises from the …